Cyclohexaneacetaldehyde, 1-ethyl- (9CI)

Base Information

• Chemical Name: Cyclohexaneacetaldehyde, 1-ethyl- (9CI)
• CAS No.: 793675-01-1
• Molecular Formula: C10H18 O
• Molecular Weight: 154.24932
• Mol file: 793675-01-1.mol

Synonyms:Cyclohexaneacetaldehyde, 1-ethyl- (9CI)

Chemical Property of Cyclohexaneacetaldehyde, 1-ethyl- (9CI)

Chemical Property:

• PSA: 17.07000
• LogP: 2.93590

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexaneacetaldehyde, 1-ethyl- (9CI)

There total 6 articles about Cyclohexaneacetaldehyde, 1-ethyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-cyano-2-cyclohexylideneacetate (6802-76-2) → (1-ethylcyclohexyl)acetaldehyde (793675-01-1)

Guidance literature:

Multi-step reaction with 6 steps

1.1: magnesium / diethyl ether / 0.5 h / 0 °C

1.2: 0.5 h

2.1: potassium hydroxide / water; ethanol / 6 h / Reflux

2.2: 4 h / Reflux

3.1: copper / 170 °C

4.1: sulfuric acid / water / 6 h / Reflux

5.1: lithium aluminium tetrahydride / diethyl ether / 0 - 20 °C

6.1: pyridinium chlorochromate / dichloromethane / 2 h / Inert atmosphere

With lithium aluminium tetrahydride; sulfuric acid; copper; magnesium; pyridinium chlorochromate; potassium hydroxide; In diethyl ether; ethanol; dichloromethane; water;

DOI:10.1039/c8ob00205c

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → (1-ethylcyclohexyl)acetaldehyde (793675-01-1)

Guidance literature:

Multi-step reaction with 7 steps

1.1: ammonium acetate; acetic acid / benzene / 6 h / Dean-Stark; Reflux

2.1: magnesium / diethyl ether / 0.5 h / 0 °C

2.2: 0.5 h

3.1: potassium hydroxide / water; ethanol / 6 h / Reflux

3.2: 4 h / Reflux

4.1: copper / 170 °C

5.1: sulfuric acid / water / 6 h / Reflux

6.1: lithium aluminium tetrahydride / diethyl ether / 0 - 20 °C

7.1: pyridinium chlorochromate / dichloromethane / 2 h / Inert atmosphere

With lithium aluminium tetrahydride; sulfuric acid; ammonium acetate; copper; magnesium; acetic acid; pyridinium chlorochromate; potassium hydroxide; In diethyl ether; ethanol; dichloromethane; water; benzene;

DOI:10.1039/c8ob00205c

Reference yield:

ethyl cyano(1-ethylcyclohexyl)acetate → (1-ethylcyclohexyl)acetaldehyde (793675-01-1)

Guidance literature:

Multi-step reaction with 5 steps

1.1: potassium hydroxide / water; ethanol / 6 h / Reflux

1.2: 4 h / Reflux

2.1: copper / 170 °C

3.1: sulfuric acid / water / 6 h / Reflux

4.1: lithium aluminium tetrahydride / diethyl ether / 0 - 20 °C

5.1: pyridinium chlorochromate / dichloromethane / 2 h / Inert atmosphere

With lithium aluminium tetrahydride; sulfuric acid; copper; pyridinium chlorochromate; potassium hydroxide; In diethyl ether; ethanol; dichloromethane; water;

DOI:10.1039/c8ob00205c

upstream raw materials:

cyclohexanone

ethyl 2-cyano-2-cyclohexylideneacetate

Downstream raw materials:

1-[2-(1-ethylcyclohexyl)ethyl]-4-(5-methylpyridin-2-yl)aminopiperidine