1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide

Base Information

• Chemical Name: 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide
• CAS No.: 56632-81-6
• Molecular Formula: C₁₆H₁₇FO₇
• Molecular Weight: 361.165
• Mol file: 56632-81-6.mol

Synonyms:1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide

Chemical Property of 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide

There total 4 articles about 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranose (84025-00-3) → 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide (56632-81-6)

Guidance literature:

With hydrogen bromide; In dichloromethane; acetic acid; for 1h;

DOI:10.1021/jm00165a015

Reference yield:

1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranose → 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide (56632-81-6)

Guidance literature:

With hydrogen bromide; In dichloromethane; at 4 ℃;

DOI:10.1021/jm00367a020

Reference yield:

1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranose (56632-81-6) → 1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl bromide (56632-81-6)

Guidance literature:

With hydrogen bromide; In dichloromethane; at 4 ℃;

DOI:10.1021/jm00151a025

upstream raw materials:

1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranose

1,3-di-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinose

Downstream raw materials:

Benzoic acid (2R,3R,4S,5R)-3-acetoxy-5-(6-chloro-purin-7-yl)-4-fluoro-tetrahydro-furan-2-ylmethyl ester

Benzoic acid (2R,3R,4S,5S)-3-acetoxy-5-(6-chloro-purin-7-yl)-4-fluoro-tetrahydro-furan-2-ylmethyl ester

6-chloro-9-(3-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine

Benzoic acid (2R,3R,4S,5S)-3-acetoxy-5-(6-chloro-purin-9-yl)-4-fluoro-tetrahydro-furan-2-ylmethyl ester