Phenol,4-[(1S)-1-ethenyl-1,5-dimethyl-4-hexen-1-yl]-

Base Information

• Chemical Name: Phenol,4-[(1S)-1-ethenyl-1,5-dimethyl-4-hexen-1-yl]-
• CAS No.: 147821-59-8
• Molecular Formula: C16H22 O
• Molecular Weight: 230.35
• Mol file: 147821-59-8.mol

Synonyms:Phenol,4-(1-ethenyl-1,5-dimethyl-4-hexenyl)-, (S)-; Phenol,4-[(1S)-1-ethenyl-1,5-dimethyl-4-hexenyl]- (9CI); (+)-Sporochnol A;(S)-(+)-Sporochnol A; Sporochnol A

Chemical Property of Phenol,4-[(1S)-1-ethenyl-1,5-dimethyl-4-hexen-1-yl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenol,4-[(1S)-1-ethenyl-1,5-dimethyl-4-hexen-1-yl]-

There total 23 articles about Phenol,4-[(1S)-1-ethenyl-1,5-dimethyl-4-hexen-1-yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(S)-4-(3,7-dimethylocta-1,6-dien-3-yl)phenyl 4-methylbenzenesulfonate → (S)-4-(3,7-dimethylocta-1,6-dien-3-yl)phenol (147821-59-8)

Guidance literature:

With potassium hydroxide; In ethanol; water; at 80 ℃; for 1h; Inert atmosphere;

DOI:10.1002/chem.202104268

Reference yield: 91.0%

(R)-1-(3,7-dimethylocta-1,6-dien-3-yl)-4-methoxybenzene (191212-50-7) → (S)-4-(3,7-dimethylocta-1,6-dien-3-yl)phenol (147821-59-8)

Guidance literature:

With methyl magnesium iodide; In diethyl ether; at 20 - 185 ℃;

DOI:10.1002/anie.201008067

Reference yield:

C12H22Zn + Toluene-4-sulfonic acid 4-[(E)-3-(diethoxy-phosphoryloxy)-1-methyl-propenyl]-phenyl ester → (R)-(-)-4-(1,5-dimethyl-1-vinyl-4-hexenyl)phenol + (S)-4-(3,7-dimethylocta-1,6-dien-3-yl)phenol (147821-59-8)

Guidance literature:

C₁₂H₂₂Zn; Toluene-4-sulfonic acid 4-[(E)-3-(diethoxy-phosphoryloxy)-1-methyl-propenyl]-phenyl ester; With (L,L)-C₃₀H₄₂N₄O₃; In tetrahydrofuran; at -78 ℃; for 48h;

With potassium hydroxide; In ethanol; at 80 ℃; Title compound not separated from byproducts;

DOI:10.1002/1521-3773(20010417)40:8<1456::AID-ANIE1456>3.0.CO;2-T

upstream raw materials:

triphenylphosphonio-1-methylethanide

lithio(trimethylsilyl)diazomethane

Methylenetriphenylphosphorane

(S)-5-(4-Methoxy-phenyl)-hexan-2-one

Downstream raw materials:

tert-butyl-[4-(1,5-dimethyl-1-vinyl-hex-4-enyl)-phenoxy]-dimethyl-silane