<1α,2α(1R^*,2R^*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylsulfonyl)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane

Base Information

• Chemical Name: <1α,2α(1R^*,2R^*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylsulfonyl)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane
• CAS No.: 108712-54-5
• Molecular Formula: C₂₄H₃₈O₃SSi
• Molecular Weight: 434.715

Synonyms:<1α,2α(1R^*,2R^*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylsulfonyl)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane

Chemical Property of <1α,2α(1R^*,2R^*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylsulfonyl)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <1α,2α(1R^*,2R^*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylsulfonyl)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane

There total 7 articles about <1α,2α(1R^*,2R^*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylsulfonyl)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

<1α,2α(1R*,2R*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylthio)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane (108712-53-4) → <1α,2α(1R*,2R*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylsulfonyl)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane (108712-54-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In diethyl ether; at 0 ℃; for 0.0833333h;

DOI:10.1021/jo00392a009

Reference yield:

N-(phenylthio)succinimide (14204-24-1) → <1α,2α(1R*,2R*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylsulfonyl)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane (108712-54-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) tri-n-butylphosphine / 1.) benzene, 5 min, 2.) benzene, RT, 2 h

2: 95 percent / m-chloroperoxybenzoic acid / diethyl ether / 0.08 h / 0 °C

With tributylphosphine; 3-chloro-benzenecarboperoxoic acid; In diethyl ether;

DOI:10.1021/jo00392a009

Reference yield:

t-butyldimethylsiyl triflate (69739-34-0) → <1α,2α(1R*,2R*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylsulfonyl)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane (108712-54-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 92 percent / 2,6-lutidine / CH₂Cl₂ / 0.25 h / Ambient temperature

2: 78 percent / methyllithium / diethyl ether / 0.5 h / 0 °C

3: 1.) tri-n-butylphosphine / 1.) benzene, 5 min, 2.) benzene, RT, 2 h

4: 95 percent / m-chloroperoxybenzoic acid / diethyl ether / 0.08 h / 0 °C

With 2,6-dimethylpyridine; tributylphosphine; methyllithium; 3-chloro-benzenecarboperoxoic acid; In diethyl ether; dichloromethane;

DOI:10.1021/jo00392a009

upstream raw materials:

<1α,2α(1R^*,2R^*)>-(+/-)-(1,1-dimethylethyl)dimethyl<<2-<2-methyl-1-<(phenylthio)methyl>-3-butenyl>-3-cyclohexen-1-yl>oxy>silane

N-(phenylthio)succinimide

t-butyldimethylsiyl triflate

2,2-Dimethyl-propionic acid (R)-2-((1R,6R)-6-hydroxy-cyclohex-2-enyl)-3-methyl-pent-4-enyl ester

Downstream raw materials:

(2S,4R,6R)-2-{(3R,4R)-2-Benzenesulfonyl-3-[(1R,6R)-6-(tert-butyl-dimethyl-silanyloxy)-cyclohex-2-enyl]-4-methyl-hex-5-enyl}-4-(tert-butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran

(2S,4R,6R)-2-{(3S,4S)-2-Benzenesulfonyl-3-[(1S,6S)-6-(tert-butyl-dimethyl-silanyloxy)-cyclohex-2-enyl]-4-methyl-hex-5-enyl}-4-(tert-butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran

<2R-<2α<γS^*,?S^*(1S^*,6S^*)>,4β,6α>>-?-<6-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexen-1-yl>-4-<<(1,1-dimethylethyl)diphenylsilyl>oxy>tetrahydro-6-methoxy-γ-(S)-methyl-2H-pyran-2-hexanol

(3S,4S)-4-[(1S,6S)-6-(tert-Butyl-dimethyl-silanyloxy)-cyclohex-2-enyl]-6-[(2R,4R,6R)-4-(tert-butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-yl]-3-methyl-hexanal

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