1,8-Dihydroxy-2-methoxy-3-methyl-anthraquinone

Base Information

Chemical Name:1,8-Dihydroxy-2-methoxy-3-methyl-anthraquinone
CAS No.:74272-75-6
Molecular Formula:C₁₆H₁₂O₅
Molecular Weight:284.268
Hs Code.:
DSSTox Substance ID:DTXSID60458462
Wikidata:Q82281738
ChEMBL ID:CHEMBL190920
Mol file:74272-75-6.mol

Synonyms:74272-75-6;1,8-Dihydroxy-2-methoxy-3-methyl-anthraquinone;1,8-Dihydroxy-2-methoxy-3-methylanthracene-9,10-dione;CHEMBL190920;SCHEMBL3186063;DTXSID60458462;AKOS015963510

Suppliers and Price of 1,8-Dihydroxy-2-methoxy-3-methyl-anthraquinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,8-DIHYDROXY-2-METHOXY-3-METHYL-ANTHRAQUINONE 95.00%
5MG
$ 500.25

Total 3 raw suppliers

Chemical Property of 1,8-Dihydroxy-2-methoxy-3-methyl-anthraquinone

Chemical Property:

PSA：83.83000
LogP:2.19020
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:284.06847348
Heavy Atom Count:21
Complexity:448

Purity/Quality:

99% ^*data from raw suppliers

1,8-DIHYDROXY-2-METHOXY-3-METHYL-ANTHRAQUINONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C(=C1OC)O)C(=O)C3=C(C2=O)C=CC=C3O

Technology Process of 1,8-Dihydroxy-2-methoxy-3-methyl-anthraquinone

There total 7 articles about 1,8-Dihydroxy-2-methoxy-3-methyl-anthraquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 58322-78-4
2-hydroxychrysophanol

: 74272-75-6
2-methoxychrysophanol

Guidance literature:: In diethyl ether; at 20 ℃;
DOI:10.1021/jm0492655

Reference yield: 75.0%

: 74272-75-6
2-methoxychrysophanol

Guidance literature:

Reference yield:

: 1-(2,2-dimethylpropionyl)-4,10-dioxatricyclo[5.2.1.0^2,6]-dec-8-ene-3,5-dione

: 74272-75-6
2-methoxychrysophanol

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / H₂SO₄ / 0.08 h / -15 °C

2: 30 percent / AlCl₃; NaCl / 4 h / 165 °C

3: 75 percent / diethyl ether / 20 °C

With aluminium trichloride; sulfuric acid; sodium chloride; In diethyl ether; 2: Fridel-Crafts acylation;
DOI:10.1021/jm0492655