5-Ethynyl-4-methoxy-2-methyl-6-(trifluoromethyl)pyrimidine

Base Information

Chemical Name:5-Ethynyl-4-methoxy-2-methyl-6-(trifluoromethyl)pyrimidine
CAS No.:792934-98-6
Molecular Formula:C₉H₇F₃N₂O
Molecular Weight:216.163
Hs Code.:
DSSTox Substance ID:DTXSID301191326
Mol file:792934-98-6.mol

Synonyms:792934-98-6;5-Ethynyl-4-methoxy-2-methyl-6-(trifluoromethyl)pyrimidine;SCHEMBL6243515;DTXSID301191326;5-ethynyl-4-methoxy-2-methyl-6-trifluoromethylpyrimidine

Suppliers and Price of 5-Ethynyl-4-methoxy-2-methyl-6-(trifluoromethyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-Ethynyl-4-methoxy-2-methyl-6-(trifluoromethyl)pyrimidine

Chemical Property:

PSA：35.01000
LogP:1.79370
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:216.05104734
Heavy Atom Count:15
Complexity:270

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=C(C(=N1)OC)C#C)C(F)(F)F

Technology Process of 5-Ethynyl-4-methoxy-2-methyl-6-(trifluoromethyl)pyrimidine

There total 2 articles about 5-Ethynyl-4-methoxy-2-methyl-6-(trifluoromethyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 792935-65-0
4-methoxy-2-methyl-6-trifluoromethyl-5-trimethylsilylethynylpyrimidine

: 792934-98-6
5-ethynyl-4-methoxy-2-methyl-6-trifluoromethylpyrimidine

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 0.5h;

Reference yield:

: methyl tert-butyl ether (MTBE)

: 792934-97-5
5-iodo-4-methoxy-2-methyl-6-trifluoromethylpyrimidine

: 792935-65-0
4-methoxy-2-methyl-6-trifluoromethyl-5-trimethylsilylethynylpyrimidine

: 1066-54-2
trimethylsilylacetylene

: 792934-98-6
5-ethynyl-4-methoxy-2-methyl-6-trifluoromethylpyrimidine

Guidance literature:: With tetrabutyl ammonium fluoride; N-ethyl-N,N-diisopropylamine; dichlorobis(triphenylphosphine)palladium[II]; copper(I) iodide; In tetrahydrofuran; water; N,N-dimethyl-formamide;