Technology Process of C20H19N3O2
There total 6 articles about C20H19N3O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C10H8BrN3O;
With
tetrakis(triphenylphosphine) palladium(0);
In
1,2-dimethoxyethane;
at 20 ℃;
for 0.666667h;
Inert atmosphere;
5-allyl-2-methoxyphenylboronic acid;
With
sodium carbonate;
In
1,2-dimethoxyethane; water;
for 16h;
Inert atmosphere;
Reflux;
DOI:10.1016/j.bmcl.2011.12.015
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: Jones reagent / acetone / 0.5 h / 0 °C / Inert atmosphere
2.1: sodium carbonate / acetonitrile / 8 h / Reflux; Inert atmosphere
3.1: boron dimethyl-trifluoro sulphide / dichloromethane; 1,2-dichloro-ethane / Reflux; Inert atmosphere
4.1: tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane / 0.67 h / 20 °C / Inert atmosphere
4.2: 16 h / Inert atmosphere; Reflux
With
Jones reagent; tetrakis(triphenylphosphine) palladium(0); boron dimethyl-trifluoro sulphide; sodium carbonate;
In
1,2-dimethoxyethane; dichloromethane; 1,2-dichloro-ethane; acetone; acetonitrile;
4.2: Suzuki-Miyaura coupling;
DOI:10.1016/j.bmcl.2011.12.015
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium carbonate / acetonitrile / 8 h / Reflux; Inert atmosphere
2.1: boron dimethyl-trifluoro sulphide / dichloromethane; 1,2-dichloro-ethane / Reflux; Inert atmosphere
3.1: tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane / 0.67 h / 20 °C / Inert atmosphere
3.2: 16 h / Inert atmosphere; Reflux
With
tetrakis(triphenylphosphine) palladium(0); boron dimethyl-trifluoro sulphide; sodium carbonate;
In
1,2-dimethoxyethane; dichloromethane; 1,2-dichloro-ethane; acetonitrile;
3.2: Suzuki-Miyaura coupling;
DOI:10.1016/j.bmcl.2011.12.015
