N-[2-chloro-5-cyano-3-[(2-hydroxyacetyl)amino]phenyl]-2-hydroxyacetamide

Base Information

Chemical Name:N-[2-chloro-5-cyano-3-[(2-hydroxyacetyl)amino]phenyl]-2-hydroxyacetamide
CAS No.:123548-57-2
Molecular Formula:C₁₁H₁₀ClN₃O₄
Molecular Weight:283.671
Hs Code.:
DSSTox Substance ID:DTXSID101186298

Synonyms:123548-57-2;SCHEMBL6439833;DTXSID101186298;ZINC00595862;N,N'-(2-Chloro-5-cyano-1,3-phenylene)bis[2-hydroxyacetamide]

Suppliers and Price of N-[2-chloro-5-cyano-3-[(2-hydroxyacetyl)amino]phenyl]-2-hydroxyacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[2-chloro-5-cyano-3-[(2-hydroxyacetyl)amino]phenyl]-2-hydroxyacetamide

Chemical Property:

XLogP3:-0.7
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:283.0359835
Heavy Atom Count:19
Complexity:367

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C=C(C(=C1NC(=O)CO)Cl)NC(=O)CO)C#N

Technology Process of N-[2-chloro-5-cyano-3-[(2-hydroxyacetyl)amino]phenyl]-2-hydroxyacetamide

There total 2 articles about N-[2-chloro-5-cyano-3-[(2-hydroxyacetyl)amino]phenyl]-2-hydroxyacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 123548-56-1
3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile

: 123548-57-2
3,5-bis(hydroxyacetylamino)-4-chlorobenzonitrile

Guidance literature:: With ammonium hydroxide; In methanol; for 2h; Ambient temperature;
DOI:10.1016/S0968-0896(98)00066-2

Reference yield:

: 34207-46-0
2-chloro-5-cyano-1,3-phenylenediamine

: 123548-57-2
3,5-bis(hydroxyacetylamino)-4-chlorobenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 29 percent / pyridine / 3 h / Ambient temperature

2: 62 percent / aq. NH₃ / methanol / 2 h / Ambient temperature

With pyridine; ammonium hydroxide; In methanol;
DOI:10.1016/S0968-0896(98)00066-2