2,3-dichloro-2,3-diphenylbutanedinitrile

Base Information

• Chemical Name: 2,3-dichloro-2,3-diphenylbutanedinitrile
• CAS No.: 52819-60-0
• Molecular Formula: C₁₆H₁₀Cl₂N₂
• Molecular Weight: 301.175
• Mol file: 52819-60-0.mol

Synonyms:2,3-dichloro-2,3-diphenylbutanedinitrile

Chemical Property of 2,3-dichloro-2,3-diphenylbutanedinitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-dichloro-2,3-diphenylbutanedinitrile

There total 3 articles about 2,3-dichloro-2,3-diphenylbutanedinitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

phenylacetonitrile (140-29-4) → 2,3-dichloro-2,3-diphenylbutanedinitrile (52819-60-0)

Guidance literature:

phenylacetonitrile; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

With methyl chlorosulfate; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.tetlet.2018.02.036

Reference yield:

2-chloro-2-phenylacetonitrile (22259-83-2) → 2,3-dichloro-2,3-diphenylbutanedinitrile (52819-60-0)

Guidance literature:

With hydrogenchloride; thionyl chloride; In chlorobenzene;

DOI:10.1021/jo00912a015

Reference yield:

phenylacetonitrile (140-29-4) → meso-2.3-dichloro-2.3-diphenyl-succinic acid dinitrile (52819-60-0)

Guidance literature:

With disulfur dichloride;

upstream raw materials:

2-chloro-2-phenylacetonitrile

phenylacetonitrile

Downstream raw materials:

diphenylfumaronitrile