(5-Phenylfuran-2-yl)methanamine

Base Information

Chemical Name:(5-Phenylfuran-2-yl)methanamine
CAS No.:39170-18-8
Molecular Formula:C₁₁H₁₁NO
Molecular Weight:173.214
Hs Code.:
European Community (EC) Number:959-937-7
UNII:R3VMP2ZB9L
ChEMBL ID:CHEMBL214859
DSSTox Substance ID:DTXSID601310365
Pharos Ligand ID:RB2S2RJCH7F4

Synonyms:(5-phenylfuran-2-yl)methanamine;39170-18-8;5-Phenyl-2-furanmethanamine;2-Furanmethanamine, 5-phenyl-;1-(5-phenyl-2-furyl)methanamine;(5-phenyl-2-furyl)methylamine;5-phenylfurfurylamine;R3VMP2ZB9L;SCHEMBL720013;CHEMBL214859;BDBM12363;DTXSID601310365;MFCD01930232;AKOS000143046;EN300-49879;Z316119992

Suppliers and Price of (5-Phenylfuran-2-yl)methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (5-Phenylfuran-2-yl)methanamine

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:173.084063974
Heavy Atom Count:13
Complexity:154

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC=C(O2)CN

Technology Process of (5-Phenylfuran-2-yl)methanamine

There total 5 articles about (5-Phenylfuran-2-yl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 13803-16-2
5-phenylfuran-2-carboxaldehyde oxime

: 39170-18-8
[(5-phenyl-2-furanyl)methyl]amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 24h;

Reference yield:

: 1899-24-7
5-bromo-2-furancarboxaldehyde

: 39170-18-8
[(5-phenyl-2-furanyl)methyl]amine

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / aq. sodium carbonate / tetrakis(triphenylphosphine)palladium⁽⁰⁾ / 1,2-dimethoxy-ethane; ethanol / 1 h / 90 °C

2: hydroxylamine hydrochloride; sodium acetate / aq. ethanol / 0.42 h / Heating

3: 46 mg / LAH / tetrahydrofuran / 24 h / 20 °C

With lithium aluminium tetrahydride; hydroxylamine hydrochloride; sodium acetate; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,2-dimethoxyethane; ethanol; 1: Suzuki coupling;
DOI:10.1021/jm060519r

Reference yield:

: 98-80-6
phenylboronic acid

: 39170-18-8
[(5-phenyl-2-furanyl)methyl]amine

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / aq. sodium carbonate / tetrakis(triphenylphosphine)palladium⁽⁰⁾ / 1,2-dimethoxy-ethane; ethanol / 1 h / 90 °C

2: hydroxylamine hydrochloride; sodium acetate / aq. ethanol / 0.42 h / Heating

3: 46 mg / LAH / tetrahydrofuran / 24 h / 20 °C

With lithium aluminium tetrahydride; hydroxylamine hydrochloride; sodium acetate; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,2-dimethoxyethane; ethanol; 1: Suzuki coupling;
DOI:10.1021/jm060519r