N,N-dimethyl-3-(4-methylphenyl)-3-morpholino-propylamine hydrochloride

Base Information

Chemical Name:N,N-dimethyl-3-(4-methylphenyl)-3-morpholino-propylamine hydrochloride
CAS No.:1346460-46-5
Molecular Formula:C₁₆H₂₆N₂O*ClH
Molecular Weight:298.856
Hs Code.:

Synonyms:N,N-dimethyl-3-(4-methylphenyl)-3-morpholino-propylamine hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N,N-dimethyl-3-(4-methylphenyl)-3-morpholino-propylamine hydrochloride

Chemical Property:

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Technology Process of N,N-dimethyl-3-(4-methylphenyl)-3-morpholino-propylamine hydrochloride

There total 4 articles about N,N-dimethyl-3-(4-methylphenyl)-3-morpholino-propylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1346460-46-5
N,N-dimethyl-3-(4-methylphenyl)-3-morpholino-propylamine hydrochloride

Guidance literature:: With toluene-4-sulfonic acid; triethylamine; In acetonitrile; at 20 ℃; for 12h;

With potassium carbonate; In acetonitrile; at 20 ℃; for 8h;

With hydrogenchloride; In ethyl acetate;

Reference yield:

: N,N-dimethyl-3-morpholino-3-(p-tolyl)propan-1-amine

: 1346460-46-5
N,N-dimethyl-3-(4-methylphenyl)-3-morpholino-propylamine hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; at 20 ℃; for 1h;
DOI:10.1016/j.ejmech.2014.08.045

Reference yield:

: 58574-60-0
3-dimethylamino-1-(4-methylphenyl)propanol

: 1346460-46-5
N,N-dimethyl-3-(4-methylphenyl)-3-morpholino-propylamine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 20 °C

2: potassium carbonate / acetonitrile / 8 h / 70 °C

3: hydrogenchloride / ethanol / 1 h / 20 °C

With hydrogenchloride; potassium carbonate; N-ethyl-N,N-diisopropylamine; In ethanol; acetonitrile;
DOI:10.1016/j.ejmech.2014.08.045