Technology Process of 3-(3,4-dimethoxy-5-isopropylphenyl)propanal
There total 11 articles about 3-(3,4-dimethoxy-5-isopropylphenyl)propanal which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 70 percent / K2CO3 / acetone / 1.5 h / Ambient temperature
2: 1.) NaH / 1.) benzene, reflux, 2 h; 2.) 3-pentanone, reflux, 2 h
3: 91 percent / various solvent(s) / 16 h / Heating
4: 100 percent / K2CO3 / methanol / 3 h / Ambient temperature
5: 1.) disiamylborane, 2.) KOH, H2O2 / 1.) THF, room temp., 5 h; 2.) THF, H2O, room temp., 2 h
6: 83 percent / Collins reagent / CH2Cl2 / 0.5 h / Ambient temperature
With
potassium hydroxide; Collins oxidation agent; dihydrogen peroxide; bis-(1,2-dimethylpropyl)borane; sodium hydride; potassium carbonate;
In
methanol; dichloromethane; acetone;
DOI:10.1016/0040-4020(82)80219-6
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 83 percent / AlCl3 / CH2Cl2 / 1.) room temp., 4 h; 2.) reflux, 15 min.
2: 95 percent / K2CO3 / acetone / 2 h / Ambient temperature
3: 1.) morpholine, sulphur, 2.) potassium hydroxide / 1.) reflux 8 h ; 2.) EtOH, reflux, 6 h
4: 1.9 g / cc. HCl / methanol / Ambient temperature
5: 24 percent / LiAlH4 / diethyl ether / 4 h / Heating
6: 83 percent / Collins reagent / CH2Cl2 / 0.5 h / Ambient temperature
With
morpholine; potassium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; Collins oxidation agent; potassium carbonate; sulfur;
hydrogenchloride;
In
methanol; diethyl ether; dichloromethane; acetone;
DOI:10.1016/0040-4020(82)80219-6
