(1R,5S,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid phenylamide

Base Information

Chemical Name:(1R,5S,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid phenylamide
CAS No.:117873-95-7
Molecular Formula:C₁₈H₂₂N₂O₃
Molecular Weight:314.384
Hs Code.:

Synonyms:(1R,5S,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid phenylamide

Suppliers and Price of (1R,5S,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid phenylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,5S,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid phenylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,5S,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid phenylamide

There total 5 articles about (1R,5S,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid phenylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.8%

: 118514-37-7
(1S,5R,7R)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carbonyl chloride

: 62-53-3
aniline

: 117873-95-7
(1R,5S,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid phenylamide

Guidance literature:: With dmap; In dichloromethane; for 8h; Ambient temperature;
DOI:10.1021/ja00185a044

Reference yield:

: 6998-83-0
trimethyl cis,cis-cyclohexane-1,3,5-tricarboxylate

: 117873-95-7
(1R,5S,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid phenylamide

Guidance literature:: Multi-step reaction with 5 steps

2: 97 percent / p-toluenesulfonic acid / xylene / 12 h / Heating

3: 84.9 percent / NH₃ / pyridine / 2 h / Ambient temperature

4: 85.8 percent / SOCl₂ / 2 h / Heating

5: 79.8 percent / DMAP / CH₂Cl₂ / 8 h / Ambient temperature

With dmap; thionyl chloride; ammonia; toluene-4-sulfonic acid; In pyridine; dichloromethane; xylene;
DOI:10.1021/ja00185a044

Reference yield:

: 118514-36-6
(1S,5R,7R)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid

: 117873-95-7
(1R,5S,7S)-1,5,7-Trimethyl-2,4-dioxo-3-aza-bicyclo[3.3.1]nonane-7-carboxylic acid phenylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 85.8 percent / SOCl₂ / 2 h / Heating

2: 79.8 percent / DMAP / CH₂Cl₂ / 8 h / Ambient temperature

With dmap; thionyl chloride; In dichloromethane;
DOI:10.1021/ja00185a044