2-methylbut-3-en-2-yl 5-methyl-2-[(2S)-pent-4-en-2-yl]phenyl ether

Base Information

• Chemical Name: 2-methylbut-3-en-2-yl 5-methyl-2-[(2S)-pent-4-en-2-yl]phenyl ether
• CAS No.: 1315379-00-0
• Molecular Formula: C₁₇H₂₄O
• Molecular Weight: 244.377
• Mol file: 1315379-00-0.mol

Synonyms:2-methylbut-3-en-2-yl 5-methyl-2-[(2S)-pent-4-en-2-yl]phenyl ether

Chemical Property of 2-methylbut-3-en-2-yl 5-methyl-2-[(2S)-pent-4-en-2-yl]phenyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methylbut-3-en-2-yl 5-methyl-2-[(2S)-pent-4-en-2-yl]phenyl ether

There total 15 articles about 2-methylbut-3-en-2-yl 5-methyl-2-[(2S)-pent-4-en-2-yl]phenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C12H16O (1315379-08-8) + 1,1-dimethyl-2-propenyl isobutyl carbonate (164513-96-6) → 2-methylbut-3-en-2-yl 5-methyl-2-[(2S)-pent-4-en-2-yl]phenyl ether (1315379-00-0)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1055/s-0030-1260532

Reference yield: 50.0%

dimethyltitanocene (1271-66-5) + (3S)-3-{4-methyl-2-[(2-methyl-1-oxopropan-2-yl)oxy]phenyl}butanal (1353001-85-0) → 2-methylbut-3-en-2-yl 5-methyl-2-[(2S)-pent-4-en-2-yl]phenyl ether (1315379-00-0)

Guidance literature:

In tetrahydrofuran; toluene; at 100 ℃; for 0.25h; Microwave irradiation;

DOI:10.1002/ejoc.201100706

Reference yield:

3-methyl-phenol (108-39-4) → 2-methylbut-3-en-2-yl 5-methyl-2-[(2S)-pent-4-en-2-yl]phenyl ether (1315379-00-0)

Guidance literature:

Multi-step reaction with 6 steps

1: tributylphosphine; 1,1'-azodicarbonyl-dipiperidine / benzene / 0.5 h / 60 °C

2: trimethylaluminum / hexane / 0.5 h / 20 °C

3: triethylamine / dichloromethane / 1 h / 0 °C

4: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 0.17 h / Reflux

5: toluene-4-sulfonic acid / water; acetonitrile / 0.33 h / Reflux

6: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 2 h / 20 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tributylphosphine; trimethylaluminum; toluene-4-sulfonic acid; triethylamine; 1,1'-azodicarbonyl-dipiperidine; In tetrahydrofuran; hexane; dichloromethane; water; acetonitrile; benzene; 1: Mitsunobu reaction / 2: Claisen rearrangement;

DOI:10.1055/s-0030-1260532

upstream raw materials:

C₁₂H₁₈O₂

C₁₄H₂₀OSi

C₁₂H₁₆O

1,1-dimethyl-2-propenyl isobutyl carbonate