ethyl N-3-cyano-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrol-2-yl formimidate

Base Information

• Chemical Name: ethyl N-3-cyano-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrol-2-yl formimidate
• CAS No.: 1313370-41-0
• Molecular Formula: C₃₁H₂₇N₅O₂
• Molecular Weight: 501.588
• Mol file: 1313370-41-0.mol

Synonyms:ethyl N-3-cyano-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrol-2-yl formimidate

Chemical Property of ethyl N-3-cyano-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrol-2-yl formimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl N-3-cyano-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrol-2-yl formimidate

There total 3 articles about ethyl N-3-cyano-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrol-2-yl formimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

2-amino-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrole-3-carbonitrile (1234705-69-1) + orthoformic acid triethyl ester (122-51-0) → ethyl N-3-cyano-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrol-2-yl formimidate (1313370-41-0)

Guidance literature:

for 6h; Reflux;

DOI:10.1016/j.ejmech.2011.04.034

Reference yield:

4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one (83-07-8) → ethyl N-3-cyano-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrol-2-yl formimidate (1313370-41-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: benzene / 6 h / 80 °C

1.2: Reflux

2.1: 6 h / Reflux

In benzene;

DOI:10.1016/j.ejmech.2011.04.034

Reference yield:

2-hydroxy-2-phenylacetophenone (119-53-9,579-44-2) → ethyl N-3-cyano-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrol-2-yl formimidate (1313370-41-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: benzene / 6 h / 80 °C

1.2: Reflux

2.1: 6 h / Reflux

In benzene;

DOI:10.1016/j.ejmech.2011.04.034

upstream raw materials:

2-amino-1-(2,4-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)-4,5-diphenyl-1H-pyrrole-3-carbonitrile

orthoformic acid triethyl ester

4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one

2-hydroxy-2-phenylacetophenone

Downstream raw materials:

5-(4-amino-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1,4-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one

5-(4-hydrazinyl-5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-1,4-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one

5-(8,9-diphenyl-7H-pyrrolo[3,2-e]tetrazolo[1,5-c]pyrimidin-7-yl)-1,4-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one

5-(8,9-diphenyl-7H-pyrrolo[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-1,4-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one