2-methoxyethyl 2,3,4-tri-O-benzyl-β-L-rhamanopyranoside

Base Information

• Chemical Name: 2-methoxyethyl 2,3,4-tri-O-benzyl-β-L-rhamanopyranoside
• CAS No.: 87908-27-8
• Molecular Formula: C₃₀H₃₆O₆
• Molecular Weight: 492.612
• Mol file: 87908-27-8.mol

Synonyms:2-methoxyethyl 2,3,4-tri-O-benzyl-β-L-rhamanopyranoside

Chemical Property of 2-methoxyethyl 2,3,4-tri-O-benzyl-β-L-rhamanopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methoxyethyl 2,3,4-tri-O-benzyl-β-L-rhamanopyranoside

There total 2 articles about 2-methoxyethyl 2,3,4-tri-O-benzyl-β-L-rhamanopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

benzyl chloride (100-44-7) + 2-methoxyethyl α-L-rhamnopyranoside (127874-98-0) → 2-methoxyethyl 2,3,4-tri-O-benzyl-β-L-rhamanopyranoside (87908-27-8)

Guidance literature:

With potassium hydroxide; at 120 ℃; for 2h;

DOI:10.1246/bcsj.62.3549

Reference yield:

2-methoxy-ethanol (109-86-4,95507-80-5) + 2,3,4-tri-O-benzyl-L-rhamnopyranose (210426-02-1) → 2-methoxyethyl 2,3,4-tri-O-benzyl-α-L-rhamanopyranoside + 2-methoxyethyl 2,3,4-tri-O-benzyl-β-L-rhamanopyranoside (87908-27-8)

Guidance literature:

With Nonafluorobutanesulfonyl fluoride; caesium carbonate; In dichloromethane; at 25 - 35 ℃; for 18h; Overall yield = 93 percent; Overall yield = 85 mg; diastereoselective reaction; Inert atmosphere; Schlenk technique; Molecular sieve; Sealed tube;

DOI:10.1016/j.tet.2020.131800

Reference yield: 78.0%

2-methoxyethyl 2,3,4-tri-O-benzyl-β-L-rhamanopyranoside (87908-27-8) → 2,3,4-tri-O-benzyl-L-rhamnopyranose (210426-02-1)

Guidance literature:

With titanium tetrachloride; In dichloromethane; for 0.0833333h; Ambient temperature;

DOI:10.1246/bcsj.62.3549

upstream raw materials:

benzyl chloride

2-methoxyethyl α-L-rhamnopyranoside

2-methoxy-ethanol

2,3,4-tri-O-benzyl-L-rhamnopyranose

Downstream raw materials:

2,3,4-tri-O-benzyl-L-rhamnopyranose