Technology Process of 2,4-Dideoxy-5-O-<(1,1-dimethylethyl)diphenylsolyl>-2,4-dimethyl-L-xylose, Cyclic 1,3-Propanediyl Mercaptal (Alcohol 8)
There total 4 articles about 2,4-Dideoxy-5-O-<(1,1-dimethylethyl)diphenylsolyl>-2,4-dimethyl-L-xylose, Cyclic 1,3-Propanediyl Mercaptal (Alcohol 8) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dmap; triethylamine;
In
dichloromethane;
for 12h;
Ambient temperature;
DOI:10.1021/jo00292a045
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 78 percent / 1) cerium trichloride heptahydrate, NaBH4, 2) p-toluene sulfonic acid / ethanol / 1) -15 deg C, 2) r.t., 1h
2: 80 percent / borane-dimethyl sulfide complex, NaOH, 30percent H2O2 / tetrahydrofuran; dimethylsulfoxide / 4 h
3: 64 percent / TiCl4 / CH2Cl2 / 1) 0 deg C, 2) r.t., 1.5h
4: 88 percent / Et3N, 4-(dimethylamino)pyridine / CH2Cl2 / 12 h / Ambient temperature
With
dmap; sodium hydroxide; sodium tetrahydroborate; cerium(III) chloride; dimethylsulfide borane complex; dihydrogen peroxide; titanium tetrachloride; toluene-4-sulfonic acid; triethylamine;
In
tetrahydrofuran; ethanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/jo00292a045
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 64 percent / TiCl4 / CH2Cl2 / 1) 0 deg C, 2) r.t., 1.5h
2: 88 percent / Et3N, 4-(dimethylamino)pyridine / CH2Cl2 / 12 h / Ambient temperature
With
dmap; titanium tetrachloride; triethylamine;
In
dichloromethane;
DOI:10.1021/jo00292a045
