(R)-2-((E)-2-Naphthalen-1-yl-vinyl)-1-((R)-1-phenyl-ethyl)-aziridine

Base Information

• Chemical Name: (R)-2-((E)-2-Naphthalen-1-yl-vinyl)-1-((R)-1-phenyl-ethyl)-aziridine
• CAS No.: 909408-48-6
• Molecular Formula: C₂₂H₂₁N
• Molecular Weight: 299.415
• Mol file: 909408-48-6.mol

Synonyms:(R)-2-((E)-2-Naphthalen-1-yl-vinyl)-1-((R)-1-phenyl-ethyl)-aziridine

Chemical Property of (R)-2-((E)-2-Naphthalen-1-yl-vinyl)-1-((R)-1-phenyl-ethyl)-aziridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-2-((E)-2-Naphthalen-1-yl-vinyl)-1-((R)-1-phenyl-ethyl)-aziridine

There total 1 articles about (R)-2-((E)-2-Naphthalen-1-yl-vinyl)-1-((R)-1-phenyl-ethyl)-aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(2S)-1-[(1R)-1-phenylethyl]aziridine-2-carbaldehyde (180196-03-6) → (R)-2-((E)-2-Naphthalen-1-yl-vinyl)-1-((R)-1-phenyl-ethyl)-aziridine (909408-48-6)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃;

DOI:10.1016/j.tet.2006.06.024

Reference yield:

(R)-2-((E)-2-Naphthalen-1-yl-vinyl)-1-((R)-1-phenyl-ethyl)-aziridine (909408-48-6) → (S)-4-Naphthalen-1-yl-N1-((R)-1-phenyl-ethyl)-butane-1,2-diamine

Guidance literature:

Multi-step reaction with 3 steps

1: Me₃SiN₃ / CH₂Cl₂

2: LiAlH₄ / diethyl ether / 0 °C

3: H₂ / Pd/C / methanol

With lithium aluminium tetrahydride; trimethylsilylazide; hydrogen; palladium on activated charcoal; In methanol; diethyl ether; dichloromethane;

DOI:10.1016/j.tet.2006.06.024

Reference yield:

(R)-2-((E)-2-Naphthalen-1-yl-vinyl)-1-((R)-1-phenyl-ethyl)-aziridine (909408-48-6) → ((Z)-(S)-2-Azido-4-naphthalen-1-yl-but-3-enyl)-((R)-1-phenyl-ethyl)-amine

Guidance literature:

With trimethylsilylazide; In dichloromethane;

DOI:10.1016/j.tet.2006.06.024

upstream raw materials:

(2S)-1-[(1R)-1-phenylethyl]aziridine-2-carbaldehyde