2,2,3-triphenyl-butyric acid

Base Information

• Chemical Name: 2,2,3-triphenyl-butyric acid
• CAS No.: 112949-16-3
• Molecular Formula: C₂₂H₂₀O₂
• Molecular Weight: 316.4
• Mol file: 112949-16-3.mol

Synonyms:2,2,3-triphenyl-butyric acid

Chemical Property of 2,2,3-triphenyl-butyric acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,3-triphenyl-butyric acid

There total 7 articles about 2,2,3-triphenyl-butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-diphenyl-1-propene (778-66-5) + iodobenzene (591-50-4) + carbon dioxide (124-38-9,18923-20-1) → 2,2,3-triphenyl-butyric acid (112949-16-3)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; potassium formate; potassium carbonate; In dimethyl sulfoxide; at 25 - 30 ℃; for 24h; under 760.051 Torr; regioselective reaction; Schlenk technique; Irradiation;

DOI:10.1021/jacs.0c03144

Reference yield:

2,2-diphenylacetic acid (117-34-0) → 2,2,3-triphenyl-butyric acid (112949-16-3)

Guidance literature:

With ammonia; sodium amide; anschliessendes Behandeln mit (+-)-1-Chlor-1-phenyl-aethan in Aether;

DOI:10.1021/ja01600a035

Reference yield:

(+/-)-methyl-(1.1.2-triphenyl-propyl)-ether (854256-42-1) → 2,2,3-triphenyl-butyric acid (112949-16-3)

Guidance literature:

With diethyl ether; sodium; anschliessendes Behandeln mit Kohlendioxid bei 0grad;

DOI:10.1039/jr9380000727

upstream raw materials:

2,2-diphenylacetic acid

(+/-)-methyl-(1.1.2-triphenyl-propyl)-ether

benzo[b]thiophen-3-yl-diphenyl-acetic acid

1,2-diphenylpropan-1-one