C₂₃H₃₁N

Base Information

• Chemical Name: C₂₃H₃₁N
• CAS No.: 238072-74-7
• Molecular Formula: C₂₃H₃₁N
• Molecular Weight: 321.506
• Mol file: 238072-74-7.mol

Synonyms:C₂₃H₃₁N

Chemical Property of C₂₃H₃₁N

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₃₁N

There total 14 articles about C₂₃H₃₁N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C21H30O (238072-73-6) + diethyl 1-cyanomethylphosphonate (2537-48-6) → C23H31N (238072-74-7) + C23H31N (238072-81-6)

Guidance literature:

diethyl 1-cyanomethylphosphonate; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.333333h;

C₂₁H₃₀O; In tetrahydrofuran; at 20 ℃; for 2h; Further stages.;

DOI:10.1021/ol990048l

Reference yield:

C10H14O3 (238072-67-8) → C23H31N (238072-74-7)

Guidance literature:

Multi-step reaction with 8 steps

1.1: NaH / tetrahydrofuran; various solvent(s) / 0.33 h / 20 °C

1.2: 91 percent / tetrahydrofuran; various solvent(s) / 1 h / 20 °C

2.1: 96 percent / K₂CO₃; MeOH / 2 h / 20 °C

3.1: 96 percent / imidazole; DMAP / CH₂Cl₂ / 2 h / 20 °C

4.1: DIBAL-H / diethyl ether; hexane / 5 h / -78 °C

5.1: BuLi / tetrahydrofuran; hexane / 0.17 h / 20 °C

5.2: 90 percent / tetrahydrofuran; hexane / 20 °C

6.1: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 4 h / 70 °C

7.1: 80 percent / SO₃-pyridine; Et₃N / dimethylsulfoxide / 0.67 h / 20 °C

8.1: NaH / tetrahydrofuran; various solvent(s) / 0.33 h / 20 °C

8.2: tetrahydrofuran; various solvent(s) / 2 h / 20 °C

With 1H-imidazole; methanol; dmap; n-butyllithium; pyridine-SO₃ complex; tetrabutyl ammonium fluoride; sodium hydride; diisobutylaluminium hydride; potassium carbonate; triethylamine; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; dimethyl sulfoxide;

DOI:10.1021/ol990048l

Reference yield:

C10H16O3 (238072-61-2) → C23H31N (238072-74-7)

Guidance literature:

Multi-step reaction with 9 steps

1.1: 98 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂ / -60 - 20 °C

2.1: NaH / tetrahydrofuran; various solvent(s) / 0.33 h / 20 °C

2.2: 91 percent / tetrahydrofuran; various solvent(s) / 1 h / 20 °C

3.1: 96 percent / K₂CO₃; MeOH / 2 h / 20 °C

4.1: 96 percent / imidazole; DMAP / CH₂Cl₂ / 2 h / 20 °C

5.1: DIBAL-H / diethyl ether; hexane / 5 h / -78 °C

6.1: BuLi / tetrahydrofuran; hexane / 0.17 h / 20 °C

6.2: 90 percent / tetrahydrofuran; hexane / 20 °C

7.1: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 4 h / 70 °C

8.1: 80 percent / SO₃-pyridine; Et₃N / dimethylsulfoxide / 0.67 h / 20 °C

9.1: NaH / tetrahydrofuran; various solvent(s) / 0.33 h / 20 °C

9.2: tetrahydrofuran; various solvent(s) / 2 h / 20 °C

With 1H-imidazole; methanol; dmap; n-butyllithium; oxalyl dichloride; pyridine-SO₃ complex; tetrabutyl ammonium fluoride; sodium hydride; diisobutylaluminium hydride; potassium carbonate; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; dimethyl sulfoxide; 1.1: Swern oxidation;

DOI:10.1021/ol990048l

upstream raw materials:

C₂₁H₃₀O

diethyl 1-cyanomethylphosphonate

C₁₀H₁₆O₃

C₁₀H₁₄O₃