Technology Process of 6-benzyloxy-7-methoxy-α-keto-3,4-benzyldihydroisoquinoline
There total 6 articles about 6-benzyloxy-7-methoxy-α-keto-3,4-benzyldihydroisoquinoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
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Multi-step reaction with 2 steps
1: 87 percent / POCl3 / CH2Cl2 / 3 h / Heating
2: 90 percent / air / Pd/C / acetonitrile / 1 h / 20 °C
With
air; trichlorophosphate;
palladium on activated charcoal;
In
dichloromethane; acetonitrile;
1: Bischler-Napieralski cyclodehydration;
DOI:10.1021/jm020831a
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 94 percent / K2CO3 / ethanol / 5 h / Heating
2: 88 percent / NH4OAc; AcOH / 4 h / Heating
3: 63 percent / LiAlH4 / diethyl ether; tetrahydrofuran / 2 h / Heating
4: 68 percent / 5percent aq. NaOH / CH2Cl2 / 2 h / 20 °C
5: 87 percent / POCl3 / CH2Cl2 / 3 h / Heating
6: 90 percent / air / Pd/C / acetonitrile / 1 h / 20 °C
With
lithium aluminium tetrahydride; air; ammonium acetate; potassium carbonate; acetic acid; trichlorophosphate;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane; acetonitrile;
4: Schotten-Baumann reaction / 5: Bischler-Napieralski cyclodehydration;
DOI:10.1021/jm020831a
