2-(7H-purin-6-yl)acetamide

Base Information

Chemical Name:2-(7H-purin-6-yl)acetamide
CAS No.:2228-05-9
Molecular Formula:C₇H₇N₅O
Molecular Weight:177.165
Hs Code.:
NSC Number:81691
DSSTox Substance ID:DTXSID10421449
Mol file:2228-05-9.mol

Synonyms:2228-05-9;2-(7H-purin-6-yl)acetamide;Purine-6-acetamide;DTXSID10421449;NSC81691;NSC-81691

Suppliers and Price of 2-(7H-purin-6-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(7H-purin-6-yl)acetamide

Chemical Property:

Vapor Pressure:2.52E-07mmHg at 25°C
Boiling Point:421.9°C at 760 mmHg
Flash Point:209°C
Density:1.75g/cm³
XLogP3:-1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:177.06505986
Heavy Atom Count:13
Complexity:209

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC2=NC=NC(=C2N1)CC(=O)N

Technology Process of 2-(7H-purin-6-yl)acetamide

There total 5 articles about 2-(7H-purin-6-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 102103-65-1
(Z)-α-(aminomethylene)-9H-purine-6-acetamide

: 2228-05-9
purine-6-acetamide

Guidance literature:: With benzylamine; In ethanol; N,N-dimethyl-formamide; for 72h; Heating;
DOI:10.1002/jhet.5570280236

Reference yield:

: 102103-62-8
α-cyanopurine-6-acetamide

: 2228-05-9
purine-6-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / H₂, methanolic NH₃ / 5percent Pd-C / dimethylformamide; benzene / 24 h / 3040 Torr / Ambient temperature

2: 88 percent / benzylamine / dimethylformamide; ethanol / 72 h / Heating

With ammonia; hydrogen; benzylamine; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide; benzene;
DOI:10.1002/jhet.5570280236

Reference yield:

: 102103-61-7
α-cyano-9-(tetrahydrofuran-2-yl)-9H-purine-6-acetamide

: 2228-05-9
purine-6-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / 3N HCl / 3 h / Ambient temperature

2: 65 percent / H₂, methanolic NH₃ / 5percent Pd-C / dimethylformamide; benzene / 24 h / 3040 Torr / Ambient temperature

3: 88 percent / benzylamine / dimethylformamide; ethanol / 72 h / Heating

With hydrogenchloride; ammonia; hydrogen; benzylamine; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide; benzene;
DOI:10.1002/jhet.5570280236