[(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine)-2-carboxamide]-2-[(3-methylpentanoyl)-amino]-3-phenylpropionic acid hydrazide

Base Information

Chemical Name:[(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine)-2-carboxamide]-2-[(3-methylpentanoyl)-amino]-3-phenylpropionic acid hydrazide
CAS No.:1638769-11-5
Molecular Formula:C₂₇H₃₄N₆O₄
Molecular Weight:506.605
Hs Code.:

Synonyms:[(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine)-2-carboxamide]-2-[(3-methylpentanoyl)-amino]-3-phenylpropionic acid hydrazide

Suppliers and Price of [(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine)-2-carboxamide]-2-[(3-methylpentanoyl)-amino]-3-phenylpropionic acid hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine)-2-carboxamide]-2-[(3-methylpentanoyl)-amino]-3-phenylpropionic acid hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine)-2-carboxamide]-2-[(3-methylpentanoyl)-amino]-3-phenylpropionic acid hydrazide

There total 5 articles about [(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine)-2-carboxamide]-2-[(3-methylpentanoyl)-amino]-3-phenylpropionic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 1638769-10-4
ethyl 2-[2-(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridin-3-yl)carboxamido-3-methylpentanoyl]amino-3-phenylpropanoate

: 1638769-11-5
[(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine)-2-carboxamide]-2-[(3-methylpentanoyl)-amino]-3-phenylpropionic acid hydrazide

Guidance literature:: With hydrazine hydrate; In methanol; for 6h; Reflux;
DOI:10.5560/ZNB.2014-4031

Reference yield:

: 389-08-2
nalidixic Acid

: 1638769-11-5
[(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine)-2-carboxamide]-2-[(3-methylpentanoyl)-amino]-3-phenylpropionic acid hydrazide

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine; chloroformic acid ethyl ester

2.1: sodium hydroxide

3.1: triethylamine; chloroformic acid ethyl ester / dichloromethane / 0.17 h / -20 °C

3.2: 3 h / -20 - 20 °C

4.1: hydrazine hydrate / methanol / 6 h / Reflux

With chloroformic acid ethyl ester; hydrazine hydrate; triethylamine; sodium hydroxide; In methanol; dichloromethane;
DOI:10.5560/ZNB.2014-4031

Reference yield:

: 18598-74-8
methyl L-isoleucinate hydrochloride

: 1638769-11-5
[(1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine)-2-carboxamide]-2-[(3-methylpentanoyl)-amino]-3-phenylpropionic acid hydrazide

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine; chloroformic acid ethyl ester

2.1: sodium hydroxide

3.1: triethylamine; chloroformic acid ethyl ester / dichloromethane / 0.17 h / -20 °C

3.2: 3 h / -20 - 20 °C

4.1: hydrazine hydrate / methanol / 6 h / Reflux

With chloroformic acid ethyl ester; hydrazine hydrate; triethylamine; sodium hydroxide; In methanol; dichloromethane;
DOI:10.5560/ZNB.2014-4031