5-acetyl-6-(2-aminoethoxy)-7-[3-(4-fluorophenyl)butoxy]-2,4-dimethylbenzo[d]oxazole hydrochloride

Base Information

Chemical Name:5-acetyl-6-(2-aminoethoxy)-7-[3-(4-fluorophenyl)butoxy]-2,4-dimethylbenzo[d]oxazole hydrochloride
CAS No.:1201582-22-0
Molecular Formula:C₂₃H₂₇FN₂O₄*ClH
Molecular Weight:450.938
Hs Code.:

Synonyms:5-acetyl-6-(2-aminoethoxy)-7-[3-(4-fluorophenyl)butoxy]-2,4-dimethylbenzo[d]oxazole hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-acetyl-6-(2-aminoethoxy)-7-[3-(4-fluorophenyl)butoxy]-2,4-dimethylbenzo[d]oxazole hydrochloride

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Technology Process of 5-acetyl-6-(2-aminoethoxy)-7-[3-(4-fluorophenyl)butoxy]-2,4-dimethylbenzo[d]oxazole hydrochloride

There total 2 articles about 5-acetyl-6-(2-aminoethoxy)-7-[3-(4-fluorophenyl)butoxy]-2,4-dimethylbenzo[d]oxazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1201582-62-8
5-acetyl-6-(2-(N-Boc-amino)ethoxy)-7-(3-(4-fluorophenyl)butoxy)-2,4-dimethylbenzo[d]oxazole

: 1201582-22-0
5-acetyl-6-(2-aminoethoxy)-7-[3-(4-fluorophenyl)butoxy]-2,4-dimethylbenzo[d]oxazole hydrochloride

Guidance literature:: With methanol; acetyl chloride; for 0.5h;

Reference yield:

: 1201582-60-6
5-acetyl-7-[3-(4-fluorophenyl)butoxy]-6-hydroxy-2,4-dimethylbenzooxazole

: 1201582-22-0
5-acetyl-6-(2-aminoethoxy)-7-[3-(4-fluorophenyl)butoxy]-2,4-dimethylbenzo[d]oxazole hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: di-isopropyl azodicarboxylate; triphenylphosphine / toluene / 1.5 h

2: methanol; acetyl chloride / 0.5 h

With methanol; di-isopropyl azodicarboxylate; acetyl chloride; triphenylphosphine; In toluene; 1: Mitsunobu reaction;