N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2-heptene

Base Information

• Chemical Name: N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2-heptene
• CAS No.: 83248-94-6
• Molecular Formula: C₁₅H₁₁F₆NO
• Molecular Weight: 335.249
• Mol file: 83248-94-6.mol

Synonyms:N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2-heptene

Chemical Property of N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2-heptene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2-heptene

There total 2 articles about N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2-heptene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2.5-heptadiene (83248-91-3) → N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2-heptene (83248-94-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; under 760 Torr;

DOI:10.1021/jo00145a037

Reference yield:

N-benzoylpyrrole (5145-65-3) → N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2-heptene (83248-94-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / tetrahydrofuran / 5 h / Heating

2: 97 percent / H₂ / 10percent Pd/C / ethanol / 760 Torr

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol;

DOI:10.1021/jo00145a037

Reference yield: 94.0%

N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2-heptene (83248-94-6) → (3,4-bis(trifluoromethyl)-1H-pyrrol-1-yl)(phenyl)methanone (83248-96-8)

Guidance literature:

In benzene; at 300 ℃;

DOI:10.1021/jo00145a037

upstream raw materials:

N-benzoyl-2,3-bis(trifluoromethyl)-7-azabicyclo<2.2.1>-2.5-heptadiene

N-benzoylpyrrole

Downstream raw materials:

(3,4-bis(trifluoromethyl)-1H-pyrrol-1-yl)(phenyl)methanone