[η²-benzyne][1,2-bis(dicyclohexylphosphino)ethane]nickel(0)

Base Information

• Chemical Name: [η²-benzyne][1,2-bis(dicyclohexylphosphino)ethane]nickel(0)
• CAS No.: 114907-51-6
• Molecular Formula: C₃₂H₅₂NiP₂
• Molecular Weight: 557.402
• Mol file: 114907-51-6.mol

Synonyms:[η²-benzyne][1,2-bis(dicyclohexylphosphino)ethane]nickel(0)

Chemical Property of [η²-benzyne][1,2-bis(dicyclohexylphosphino)ethane]nickel(0)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [η²-benzyne][1,2-bis(dicyclohexylphosphino)ethane]nickel(0)

There total 11 articles about [η²-benzyne][1,2-bis(dicyclohexylphosphino)ethane]nickel(0) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

cis-bromo[1,2-bis(dicyclohexylphosphino)ethane][2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]nickel(II) (447405-46-1) → [η2-benzyne][1,2-bis(dicyclohexylphosphino)ethane]nickel(0) (114907-51-6)

Guidance literature:

With t-C₄H₉OK; In tetrahydrofuran; the mixt. in THF was stirred at room temp. for 2 h (N2); the solvent was removed in vac., the residue was washed with hexane;

DOI:10.1021/ja0264091

Reference yield: 72.0%

NiCl(C6H4Br)((C6H11)2PCH2CH2P(C6H11)2)*0.5C4H8O (97921-16-9) → [η2-benzyne][1,2-bis(dicyclohexylphosphino)ethane]nickel(0) (114907-51-6)

Guidance literature:

With Na#Hg; In tetrahydrofuran; mixt. of Ni-complex and Na amalgam in THF was stirred under N2 for 3.5 h; soln. was evapd., residue extd. with hot cyclohexane, ext. filtered, evapd., residue was triturated with hexane, redissolved in hot cyclohexane, soln. filtered, concd., hexane was added, crystals were filtered off, washed with hexane; elem. anal.;

Reference yield: 60.0%

Ni[(C6H4Br)P[(C6H11)2CH2CH2P(C6H11)2]Cl] (97921-16-9) → [η2-benzyne][1,2-bis(dicyclohexylphosphino)ethane]nickel(0) (114907-51-6)

Guidance literature:

With sodium amalgam or NaC₁₀H₈; In not given;

DOI:10.1016/0022-328X(86)84053-0

upstream raw materials:

Ni[(C₆H₄Br)P[(C₆H₁₁)2CH₂CH₂P(C₆H₁₁)2]Cl]

NiCl(C₆H₄Br)((C₆H₁₁)2PCH₂CH₂P(C₆H₁₁)2)*0.5C₄H₈O

cis-bromo[1,2-bis(dicyclohexylphosphino)ethane][2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]nickel(II)

fluorobenzene

Downstream raw materials:

Ni(O₂CCF₃)2((C₆H₁₁)2PCH₂CH₂P(C₆H₁₁)2)

Ni(C₆H₅CCC₆H₅)((C₆H₁₁)2PCH₂CH₂P(C₆H₁₁)2)

NiI(C₆H₅)((C₆H₁₁)2PCH₂CH₂P(C₆H₁₁)2)

NiI(C₆H₄CH₃)((C₆H₁₁)2PCH₂CH₂P(C₆H₁₁)2)