Technology Process of 5-(1-benzylpyrrolidin-2-yl)-2-methoxypyridine
There total 3 articles about 5-(1-benzylpyrrolidin-2-yl)-2-methoxypyridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium carbonate;
In
water;
at 110 ℃;
for 2h;
Inert atmosphere;
Microwave irradiation;
Green chemistry;
DOI:10.1055/s-0032-1316859
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium tetrahydroborate / methanol / 2 h / 0 °C
2: bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium carbonate / water / 2 h / 110 °C / Inert atmosphere; Microwave irradiation; Green chemistry
With
sodium tetrahydroborate; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium carbonate;
In
methanol; water;
DOI:10.1055/s-0032-1316859
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / diethyl ether; hexane / 0.25 h / -78 °C / Inert atmosphere
1.2: 2 h
2.1: sodium tetrahydroborate / methanol / 2 h / 0 °C
3.1: bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium carbonate / water / 2 h / 110 °C / Inert atmosphere; Microwave irradiation; Green chemistry
With
sodium tetrahydroborate; n-butyllithium; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium carbonate;
In
methanol; diethyl ether; hexane; water;
DOI:10.1055/s-0032-1316859
