C₂₂H₂₃NO

Base Information

• Chemical Name: C₂₂H₂₃NO
• CAS No.: 1426129-51-2
• Molecular Formula: C₂₂H₂₃NO
• Molecular Weight: 317.431
• Mol file: 1426129-51-2.mol

Synonyms:C₂₂H₂₃NO

Chemical Property of C₂₂H₂₃NO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₃NO

There total 2 articles about C₂₂H₂₃NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(R)-2-benzoylamino-3-biphenyl-4-yl-propionic acid methyl ester (1446104-51-3) → C22H23NO (1426129-51-2)

Guidance literature:

(R)-2-benzoylamino-3-biphenyl-4-yl-propionic acid methyl ester; With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Reflux;

With water; In tetrahydrofuran; at 20 ℃;

Reference yield:

C23H19NO3 → C22H23NO (1426129-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; (S)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']-dinaphthalen-4-yl)piperidine; hydrogen / dichloromethane / 25 °C / 7500.75 Torr

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / Reflux

2.2: 20 °C

With lithium aluminium tetrahydride; bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; hydrogen; (S)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']-dinaphthalen-4-yl)piperidine; In tetrahydrofuran; dichloromethane;

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + C22H23NO (1426129-51-2) → N-[(1R)-2-[1,1'-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid tert-butyl ester (1426129-50-1)

Guidance literature:

With palladium on activated charcoal; hydrogen; In tetrahydrofuran; at 30 ℃; for 18h; under 3750.38 Torr;

upstream raw materials:

(R)-2-benzoylamino-3-biphenyl-4-yl-propionic acid methyl ester

Downstream raw materials:

N-[(1R)-2-[1,1'-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid tert-butyl ester