1,2,3,3abeta,8,8abeta-Hexahydropyrrolo[2,3-b]indole-1,2alpha-dicarboxylic acid dimethyl ester

Base Information

Chemical Name:1,2,3,3abeta,8,8abeta-Hexahydropyrrolo[2,3-b]indole-1,2alpha-dicarboxylic acid dimethyl ester
CAS No.:79465-87-5
Molecular Formula:C₁₄H₁₆N₂O₄
Molecular Weight:276.292
Hs Code.:
Nikkaji Number:J510.812H
Mol file:79465-87-5.mol

Synonyms:1,2,3,3abeta,8,8abeta-Hexahydropyrrolo[2,3-b]indole-1,2alpha-dicarboxylic acid dimethyl ester

Suppliers and Price of 1,2,3,3abeta,8,8abeta-Hexahydropyrrolo[2,3-b]indole-1,2alpha-dicarboxylic acid dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 1,2,3,3abeta,8,8abeta-Hexahydropyrrolo[2,3-b]indole-1,2alpha-dicarboxylic acid dimethyl ester

Chemical Property:

PSA：67.87000
LogP:1.61140
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:276.11100700
Heavy Atom Count:20
Complexity:414

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1CC2C(N1C(=O)OC)NC3=CC=CC=C23
Isomeric SMILES:COC(=O)[C@@H]1C[C@H]2[C@@H](N1C(=O)OC)NC3=CC=CC=C23

Technology Process of 1,2,3,3abeta,8,8abeta-Hexahydropyrrolo[2,3-b]indole-1,2alpha-dicarboxylic acid dimethyl ester

There total 3 articles about 1,2,3,3abeta,8,8abeta-Hexahydropyrrolo[2,3-b]indole-1,2alpha-dicarboxylic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 66377-68-2
N_b-methoxycarbonyl-DL-tryptophan methyl ester

: 67811-38-5,79465-82-0,79465-87-5,136088-17-0,146235-39-4
DL-(2β,3aα,8aα)-1,2,3,3a,8,8a-hexahydro-1,2-dimethoxycarbonylpyrrolo<2,3-b>indole

Guidance literature:: With phosphoric acid; for 3h; Ambient temperature;
DOI:10.1016/S0040-4020(01)92088-5

Reference yield:

: 66377-68-2
N_b-methoxycarbonyl-DL-tryptophan methyl ester

: 67811-38-5,79465-82-0,79465-87-5,136088-17-0,146235-39-4
DL-(2β,3aα,8aα)-1,2,3,3a,8,8a-hexahydro-1,2-dimethoxycarbonylpyrrolo<2,3-b>indole

: 67811-38-5,79465-82-0,79465-87-5,136088-17-0,146235-39-4
DL-(2β,3aβ,8aβ)-1,2,3,3a,8,8a-hexahydro-1,2-dimethoxycarbonylpyrrolo<2,3-b>indole

Guidance literature:: With phosphoric acid; for 3h; Product distribution; Mechanism; Ambient temperature; variation of acids, reaction times and temperatures;
DOI:10.1016/S0040-4020(01)92088-5

Reference yield:

: 66377-68-2
N_b-methoxycarbonyl-DL-tryptophan methyl ester

: 67811-38-5,79465-82-0,79465-87-5,136088-17-0,146235-39-4
DL-(2β,3aα,8aα)-1,2,3,3a,8,8a-hexahydro-1,2-dimethoxycarbonylpyrrolo<2,3-b>indole

: 67811-38-5,79465-82-0,79465-87-5,136088-17-0,146235-39-4
DL-(2β,3aβ,8aβ)-1,2,3,3a,8,8a-hexahydro-1,2-dimethoxycarbonylpyrrolo<2,3-b>indole

Guidance literature:: With phosphoric acid; for 3h; Product distribution; Mechanism; Ambient temperature; variation of acids, reaction times and temperatures;
DOI:10.1016/S0040-4020(01)92088-5