Technology Process of 11-<(2,6-diisopropylphenyl)carbamoyl>-6,11-dihydrodibenzoxepin-2-carboxylic acid
There total 5 articles about 11-<(2,6-diisopropylphenyl)carbamoyl>-6,11-dihydrodibenzoxepin-2-carboxylic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
methanol;
for 0.0833333h;
Heating;
DOI:10.1021/jm00032a014
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 60 percent / NaH / dimethylsulfoxide; tetrahydrofuran / 10 h / Ambient temperature
2: 9.2 g / BF3*Et2O / CH2Cl2 / 5 h
3: 9.42 g / KMnO4 / acetone; 2-methyl-propan-2-ol / 1.5 h / pH 6.86
4: 1.) SOCl2, 2.) NEt3 / 1.) CH2Cl2, 2.) CH2Cl2
5: 92 percent / 5N aq.NaOH / methanol / 0.08 h / Heating
With
sodium hydroxide; potassium permanganate; thionyl chloride; boron trifluoride diethyl etherate; sodium hydride; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; acetone; tert-butyl alcohol;
DOI:10.1021/jm00032a014
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 9.42 g / KMnO4 / acetone; 2-methyl-propan-2-ol / 1.5 h / pH 6.86
2: 1.) SOCl2, 2.) NEt3 / 1.) CH2Cl2, 2.) CH2Cl2
3: 92 percent / 5N aq.NaOH / methanol / 0.08 h / Heating
With
sodium hydroxide; potassium permanganate; thionyl chloride; triethylamine;
In
methanol; acetone; tert-butyl alcohol;
DOI:10.1021/jm00032a014
![6,11-Dihydro-N-(2,6-diisopropylphenyl)-2-methoxycarbonyl-dibenz[b,e]oxepin-11-carboxamide](/Databaselist/images/loading.webp)
