C₅₁H₇₅N₁₂O₁₈P

Base Information

• Chemical Name: C₅₁H₇₅N₁₂O₁₈P
• CAS No.: 508234-89-7
• Molecular Formula: C₅₁H₇₅N₁₂O₁₈P
• Molecular Weight: 1175.2
• Mol file: 508234-89-7.mol

Synonyms:C₅₁H₇₅N₁₂O₁₈P

Chemical Property of C₅₁H₇₅N₁₂O₁₈P

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₁H₇₅N₁₂O₁₈P

There total 14 articles about C₅₁H₇₅N₁₂O₁₈P which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Di(tert-butyl)-N-(2-cyanoethyl)-N,N'-(ethan-1,2-diyl)bis (187745-72-8) → C51H75N12O18P (508234-89-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 100 percent / H₂; KOH / Raney Ni / ethanol / 5 h / 2250.18 Torr

2: 80 percent / dicyclohexylcarbodiimide / CH₂Cl₂ / 3 h / 20 °C

3: 96 percent / aq. NaOH / tetrahydrofuran / 1 h

4: dicyclohexylcarbodiimide / CH₂Cl₂ / 0.5 h / 20 °C

5: 52 mg / aq. NaHCO₃; aq. NaOH / acetonitrile / 1 h / pH 8

With potassium hydroxide; sodium hydroxide; hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; nickel; In tetrahydrofuran; ethanol; dichloromethane; acetonitrile;

DOI:10.1016/S0968-0896(02)00311-5

Reference yield:

[2-(2-cyano-ethylamino)-ethyl]-carbamic acid tert-butyl ester (1019333-23-3) → C51H75N12O18P (508234-89-7)

Guidance literature:

Multi-step reaction with 6 steps

1: 12.90 g / CH₂Cl₂ / 12 h / 20 °C

2: 100 percent / H₂; KOH / Raney Ni / ethanol / 5 h / 2250.18 Torr

3: 80 percent / dicyclohexylcarbodiimide / CH₂Cl₂ / 3 h / 20 °C

4: 96 percent / aq. NaOH / tetrahydrofuran / 1 h

5: dicyclohexylcarbodiimide / CH₂Cl₂ / 0.5 h / 20 °C

6: 52 mg / aq. NaHCO₃; aq. NaOH / acetonitrile / 1 h / pH 8

With potassium hydroxide; sodium hydroxide; hydrogen; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; nickel; In tetrahydrofuran; ethanol; dichloromethane; acetonitrile;

DOI:10.1016/S0968-0896(02)00311-5

Reference yield:

N2-isobutyryl-2'-deoxyguanosine (64350-24-9) → C51H75N12O18P (508234-89-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 87 percent / TsOH*H₂O / dimethylformamide / 10 h

2: tetrazole / acetonitrile / 0.42 h / 0 - 20 °C

3: 100 mg / I₂; pyridine / acetonitrile; tetrahydrofuran; H₂O / 0.42 h / 0 - 20 °C

4: TFA / CH₂Cl₂ / 0.5 h

5: 52 mg / aq. NaHCO₃; aq. NaOH / acetonitrile / 1 h / pH 8

With pyridine; 1H-tetrazole; sodium hydroxide; iodine; sodium hydrogencarbonate; toluene-4-sulfonic acid; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1016/S0968-0896(02)00311-5

upstream raw materials:

N²-isobutyryl-2'-deoxyguanosine

4-bromomethyl-3-nitrobenzoic acid

4-(hydroxymethyl)-3-nitrobenzoic acid

Di(tert-butyl)-N-(3-aminopropyl)-N,N'-(ethan-1,2-diyl)bis