C₄₁H₄₈N₂O₈

Base Information

• Chemical Name: C₄₁H₄₈N₂O₈
• CAS No.: 1330629-86-1
• Molecular Formula: C₄₁H₄₈N₂O₈
• Molecular Weight: 696.841
• Mol file: 1330629-86-1.mol

Synonyms:C₄₁H₄₈N₂O₈

Chemical Property of C₄₁H₄₈N₂O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₁H₄₈N₂O₈

There total 4 articles about C₄₁H₄₈N₂O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) + 2-amino-3,4,6-tri-O-benzyl-2-deoxy-D-glucopyranose (10583-62-7) → C41H48N2O8 (1330629-86-1)

Guidance literature:

N-tert-butoxycarbonyl-L-phenylalanine; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

2-amino-3,4,6-tri-O-benzyl-2-deoxy-D-glucopyranose; With 4-methyl-morpholine; In tetrahydrofuran; at 0 - 20 ℃; for 26h; pH=9;

DOI:10.1016/j.carres.2011.04.010

Reference yield:

N-Acetyl-D-glucosamine (7512-17-6,72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4) → C41H48N2O8 (1330629-86-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: barium hydroxide octahydrate; barium(II) oxide

2.1: hydrogenchloride / tetrahydrofuran; water

3.1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

3.2: 26 h / 0 - 20 °C / pH 9

With hydrogenchloride; barium hydroxide octahydrate; benzotriazol-1-ol; dicyclohexyl-carbodiimide; barium(II) oxide; In tetrahydrofuran; water;

DOI:10.1016/j.carres.2011.04.010

Reference yield:

Benzyl 2-N-acetylamino-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoside (4171-69-1) → C41H48N2O8 (1330629-86-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrogenchloride / tetrahydrofuran; water

2.1: benzotriazol-1-ol; dicyclohexyl-carbodiimide / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

2.2: 26 h / 0 - 20 °C / pH 9

With hydrogenchloride; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; water;

DOI:10.1016/j.carres.2011.04.010

upstream raw materials:

Benzyl 2-N-acetylamino-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoside

N-Acetyl-D-glucosamine

N-tert-butoxycarbonyl-L-phenylalanine

2-amino-3,4,6-tri-O-benzyl-2-deoxy-D-glucopyranose

Downstream raw materials:

C₅₂H₅₉N₃O₁₁