Technology Process of 4,6-di-O-benzyl-2,3-dideoxy-2-hexyl-3-tridecyl-D-glucono-1,5-lactone
There total 11 articles about 4,6-di-O-benzyl-2,3-dideoxy-2-hexyl-3-tridecyl-D-glucono-1,5-lactone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide;
In
dichloromethane;
at 20 ℃;
for 5h;
Inert atmosphere;
Molecular sieve;
DOI:10.1002/ejoc.201200513
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: acetyl chloride / methanol / 4.5 h / 0 - 20 °C / Inert atmosphere; Reflux
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C / Inert atmosphere
2.2: 17 h / 0 - 20 °C / Inert atmosphere
3.1: sulfuric acid / water; acetone / 3 h / 20 °C / Inert atmosphere; Reflux
4.1: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / dichloromethane / 5 h / 20 °C / Inert atmosphere; Molecular sieve
With
tetrapropylammonium perruthennate; sulfuric acid; sodium hydride; 4-methylmorpholine N-oxide; acetyl chloride;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide; acetone; mineral oil;
DOI:10.1002/ejoc.201200513
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: boron trifluoride diethyl etherate; diisobutylaluminium hydride / dichloromethane; toluene / 4 h / -78 - 20 °C / Inert atmosphere
2.1: dimethylsulfide borane complex / tetrahydrofuran / 25.5 h / 0 - 20 °C / Inert atmosphere
2.2: 1.5 h / Inert atmosphere; Reflux
3.1: acetyl chloride / methanol / 4.5 h / 0 - 20 °C / Inert atmosphere; Reflux
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C / Inert atmosphere
4.2: 17 h / 0 - 20 °C / Inert atmosphere
5.1: sulfuric acid / water; acetone / 3 h / 20 °C / Inert atmosphere; Reflux
6.1: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / dichloromethane / 5 h / 20 °C / Inert atmosphere; Molecular sieve
With
tetrapropylammonium perruthennate; dimethylsulfide borane complex; sulfuric acid; boron trifluoride diethyl etherate; sodium hydride; diisobutylaluminium hydride; 4-methylmorpholine N-oxide; acetyl chloride;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetone; toluene; mineral oil;
DOI:10.1002/ejoc.201200513
