(2R,5R)-2-(3-((benzyloxy)methyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl acetate

Base Information

• Chemical Name: (2R,5R)-2-(3-((benzyloxy)methyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl acetate
• CAS No.: 1158951-44-0
• Molecular Formula: C₂₀H₂₄N₂O₈
• Molecular Weight: 420.419
• Mol file: 1158951-44-0.mol

Synonyms:(2R,5R)-2-(3-((benzyloxy)methyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl acetate

Chemical Property of (2R,5R)-2-(3-((benzyloxy)methyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl acetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (2R,5R)-2-(3-((benzyloxy)methyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl acetate

There total 1 articles about (2R,5R)-2-(3-((benzyloxy)methyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C39H38N2O8 → (2R,5R)-2-(3-((benzyloxy)methyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl acetate (1158951-44-0)

Guidance literature:

With boron trifluoride diethyl etherate; para-thiocresol; In dichloromethane; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ol900458w

Reference yield:

(2R,5R)-2-(3-((benzyloxy)methyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl acetate (1158951-44-0) → C20H22N2O8

Guidance literature:

With dichloro-acetic acid; dimethyl sulfoxide; dicyclohexyl-carbodiimide; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ol900458w

Reference yield:

dichloro-acetic acid (79-43-6) + (2R,5R)-2-(3-((benzyloxy)methyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl acetate (1158951-44-0) → C22H24Cl2N2O9

Guidance literature:

With diisopropyl-carbodiimide; In dichloromethane; dimethyl sulfoxide; at 0 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.jmedchem.0c00545