Technology Process of C25H26FN3O3
There total 9 articles about C25H26FN3O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
caesium carbonate;
tetrakis(triphenylphosphine) palladium(0);
In
acetonitrile;
at 120 ℃;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sodium hydroxide; water; dihydrogen peroxide / methanol / 3.33 h / 15 - 20 °C
2: toluene-4-sulfonic acid hydrazide / ethanol / 2.92 h / 20 - 55 °C
3: sodium hydroxide; bromine; water / 1,4-dioxane / 2.08 h / -5 - 0 °C
4: caesium carbonate / N,N-dimethyl-formamide / 20 °C
5: diethylamine; copper(l) iodide / bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C
6: triethylamine / dichloromethane / 1 h / 20 °C
7: caesium carbonate / tetrakis(triphenylphosphine) palladium(0) / acetonitrile / 120 °C
With
copper(l) iodide; water; dihydrogen peroxide; bromine; caesium carbonate; diethylamine; triethylamine; toluene-4-sulfonic acid hydrazide; sodium hydroxide;
bis-triphenylphosphine-palladium(II) chloride; tetrakis(triphenylphosphine) palladium(0);
In
1,4-dioxane; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 100 °C
2: sodium hydroxide; water; dihydrogen peroxide / dimethyl sulfoxide; methanol / 1 h / 20 °C
3: caesium carbonate / tetrakis(triphenylphosphine) palladium(0) / acetonitrile / 120 °C
With
water; dihydrogen peroxide; caesium carbonate; N-ethyl-N,N-diisopropylamine; sodium hydroxide;
tetrakis(triphenylphosphine) palladium(0);
In
methanol; dimethyl sulfoxide; acetonitrile;