benzyl(3-methylbut-3-en-1-yl)carbamic chloride

Base Information

• Chemical Name: benzyl(3-methylbut-3-en-1-yl)carbamic chloride
• CAS No.: 1207280-40-7
• Molecular Formula: C₁₃H₁₆ClNO
• Molecular Weight: 237.729
• Mol file: 1207280-40-7.mol

Synonyms:benzyl(3-methylbut-3-en-1-yl)carbamic chloride

Chemical Property of benzyl(3-methylbut-3-en-1-yl)carbamic chloride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of benzyl(3-methylbut-3-en-1-yl)carbamic chloride

There total 5 articles about benzyl(3-methylbut-3-en-1-yl)carbamic chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(trichloromethyl) carbonate (32315-10-9) + benzyl-(3-methyl-but-3-enyl)-amine (32018-58-9) → benzyl(3-methylbut-3-en-1-yl)carbamic chloride (1207280-40-7)

Guidance literature:

With pyridine; In dichloromethane; at -78 - 20 ℃; for 5h; Inert atmosphere;

DOI:10.1021/acs.orglett.0c01197

Reference yield:

2-methyl-1-buten-4-ol (763-32-6) → benzyl(3-methylbut-3-en-1-yl)carbamic chloride (1207280-40-7)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine; dmap / dichloromethane / 20 °C / Inert atmosphere

2: ethanol / 75 °C / Inert atmosphere

3: pyridine / dichloromethane / 5 h / -78 - 20 °C / Inert atmosphere

With pyridine; dmap; triethylamine; In ethanol; dichloromethane;

DOI:10.1021/acs.orglett.0c01197

Reference yield:

benzylamine (100-46-9) → benzyl(3-methylbut-3-en-1-yl)carbamic chloride (1207280-40-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: neat (no solvent) / 6 h / 80 °C

2.1: pyridine / dichloromethane / 0.08 h / -20 °C

2.2: -20 - 20 °C

With pyridine; In dichloromethane;

DOI:10.1021/jacs.0c09949

upstream raw materials:

bis(trichloromethyl) carbonate

benzyl-(3-methyl-but-3-enyl)-amine

2-methyl-1-buten-4-ol

isopentenyl tosylate

Downstream raw materials:

1-benzyl-1,6-dihydro-4-methylpyridin-2(3H)-one

1-benzyl-5,6-dihydro-4-methylpyridin-2(1H)-one