(+/-)-MEVALONOLACTONE-1-13C

Base Information

• Chemical Name: (+/-)-MEVALONOLACTONE-1-13C
• CAS No.: 73834-54-5
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 136.078
• Mol file: 73834-54-5.mol

Synonyms:MEVALONIC-1-13C LACTONE;(+/-)-MEVALONOLACTONE-1-13C;DL-MEVALONIC ACID LACTONE-1-13C;MEVALONOLACTONE-1-13C, 99 ATOM % 13C, 98% CP;dl-mevalonic-1-13c lactone

Chemical Property of (+/-)-MEVALONOLACTONE-1-13C

Chemical Property:

• Melting Point: 28 °C(lit.)
• Refractive Index: n20/D 1.473(lit.)
• Boiling Point: 150 °C5 mm Hg(lit.)
• PSA: 46.53000
• LogP: 0.07440
• Storage Temp.: 2-8°C

Purity/Quality:

MEVALONOLACTONE-1-13C 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (+/-)-MEVALONOLACTONE-1-13C

There total 2 articles about (+/-)-MEVALONOLACTONE-1-13C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

sodium [1,2-13C2]acetate (56374-56-2) → [U-(13)C6]-mevalonolactone (287111-36-8,73834-54-5)

Guidance literature:

sodium [1,2-13C₂]acetate; With Neurospora crassa acetoacetyl-CoA thiolase; Neurospora crassa acetyl-CoA synthase; Neurospora crassa hydroxymethylglutaryl-CoA reductase; Neurospora crassa hydroxymethylglutaryl-CoA synthase; ATP; coenzyme A; NADPH; magnesium chloride; at 28 ℃; for 8h; pH=7.5; Enzymatic reaction;

With hydrogenchloride; In water; at 20 ℃; for 0.5h;

DOI:10.1271/bbb.100733

Reference yield:

D-[1,2,3,4,5,6-13C6]glucose (101615-89-8,120388-24-1,201741-04-0,478518-62-6,478529-32-7,478529-46-3,138079-87-5,478518-58-0,478519-02-7,478518-64-8,478529-73-6,74134-89-7) → [U-(13)C6]-mevalonolactone (287111-36-8,73834-54-5)

Guidance literature:

With Saccharomycopsis fibuligera; at 26 ℃; for 144h;

DOI:10.1271/bbb.100733

upstream raw materials:

sodium [1,2-13C₂]acetate

D-[1,2,3,4,5,6-¹³C₆]glucose

Refernces