Benzenesulfonamide, N-[(1R)-2-hydroxy-1-methylethyl]-4-methyl- (9CI)

Base Information

Chemical Name:Benzenesulfonamide, N-[(1R)-2-hydroxy-1-methylethyl]-4-methyl- (9CI)
CAS No.:786709-32-8
Molecular Formula:C10H15 N O3 S
Molecular Weight:229.3
Hs Code.:2935009090
Mol file:786709-32-8.mol

Synonyms:Benzenesulfonamide, N-[(1R)-2-hydroxy-1-methylethyl]-4-methyl- (9CI)

Suppliers and Price of Benzenesulfonamide, N-[(1R)-2-hydroxy-1-methylethyl]-4-methyl- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Tosyl-D-alaninol
100mg
$ 65.00

Crysdot
(R)-N-(1-Hydroxypropan-2-yl)-4-methylbenzenesulfonamide 97%
5g
$ 677.00

Total 2 raw suppliers

Chemical Property of Benzenesulfonamide, N-[(1R)-2-hydroxy-1-methylethyl]-4-methyl- (9CI)

Chemical Property:

PSA：74.78000
LogP:2.12580

Purity/Quality:

99% ^*data from raw suppliers

N-Tosyl-D-alaninol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzenesulfonamide, N-[(1R)-2-hydroxy-1-methylethyl]-4-methyl- (9CI)

There total 6 articles about Benzenesulfonamide, N-[(1R)-2-hydroxy-1-methylethyl]-4-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (Z)-(R)-4-(Toluene-4-sulfonylamino)-pent-2-ene-1-sulfinic acid methyl ester

: 786709-32-8
(R)-N-(1-hydroxypropan-2-yl)-4-methylbenzenesulfonamide

Guidance literature:: (Z)-(R)-4-(Toluene-4-sulfonylamino)-pent-2-ene-1-sulfinic acid methyl ester; With ozone; In methanol; at -78 ℃; for 0.75h;

With sodium tetrahydroborate; In methanol; at -78 - 20 ℃;
DOI:10.1021/jo0490245

Reference yield:

: (Z)-(2S,5R)-5-(Toluene-4-sulfonylamino)-hex-3-ene-2-sulfinic acid methyl ester

: 786709-32-8
(R)-N-(1-hydroxypropan-2-yl)-4-methylbenzenesulfonamide

Guidance literature:: (Z)-(2S,5R)-5-(Toluene-4-sulfonylamino)-hex-3-ene-2-sulfinic acid methyl ester; With ozone; In methanol; at -78 ℃; for 0.75h;

With sodium tetrahydroborate; In methanol; at -78 - 20 ℃;
DOI:10.1021/jo0490245

Reference yield:

: 4104-47-6
N-sulfinyl-p-toluenesulfonamide

: 786709-32-8
(R)-N-(1-hydroxypropan-2-yl)-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: (R)-2,2'-isopropylidenebis(4-phenyl-2-oxazoline); Cu(OTf)2 / CH₂Cl₂ / 22 h / -85 °C

2.1: 0.5 h / 20 °C

3.1: O₃ / methanol / 0.75 h / -78 °C

3.2: NaBH₄ / methanol / -78 - 20 °C

With copper(II) bis(trifluoromethanesulfonate); ozone; (4R,4'R)-2,2'-(propane-2,2'diyl)bis(4-phenyl-4,5-dihydrooxazole); In methanol; dichloromethane; 1.1: hetero-Diels-Alder reaction;
DOI:10.1021/jo0490245