1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-ethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene

Base Information

Chemical Name:1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-ethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene
CAS No.:444689-09-2
Molecular Formula:C₃₀H₂₀F₆OS₂
Molecular Weight:574.611
Hs Code.:

Synonyms:1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-ethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene

Suppliers and Price of 1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-ethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-ethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-ethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene

There total 9 articles about 1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-ethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1234908-69-0
1-[5-(4-ethoxyphenyl)-2-methylthienyl-3-yl]-2-{2-methyl-5-[4-(trimethylsilyl-ethynyl)phenyl]thien-3-yl}-3,3,4,4,5,5-hexafluorocyclopentene

: 444689-09-2
1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-ethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene

Guidance literature:: With sodium hydroxide; In methanol; at 20 ℃; for 2.5h;
DOI:10.1002/asia.200900503

Reference yield: 89.0%

: 1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-triisopropylsilylethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene

: 444689-09-2
1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-ethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene

Guidance literature:: With tetrabutyl ammonium fluoride; silica gel; In tetrahydrofuran; for 1h;
DOI:10.1021/ja026327c

Reference yield:

: 154566-69-5
3-bromo-2-methylthiophene-5-boronic acid

: 444689-09-2
1-[5'-(4''-methoxyphenyl)-2'-methylthien-3'-yl]-2-[2'-methyl-5'-(4''-ethynylphenyl)thien-3'-yl]-3,3,4,4,5,5-hexafluorocyclopentene

Guidance literature:: Multi-step reaction with 3 steps

1.1: 66 percent / sodium carbonate / tetrakis(triphenylphosphine)palladium⁽⁰⁾ / H₂O; tetrahydrofuran / 2.5 h / Heating

2.1: butyllithium / tetrahydrofuran / 0.25 h / -78 °C

2.2: 81 percent / tetrahydrofuran / 1.5 h / -78 - 20 °C

3.1: 89 percent / tetrabutylammonium fluoride/silica gel / tetrahydrofuran / 1 h

With n-butyllithium; tetrabutyl ammonium fluoride; silica gel; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; water;
DOI:10.1021/ja026327c