(S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-phenoxy]-phenyl}-propionic acid benzyl ester

Base Information

Chemical Name:(S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-phenoxy]-phenyl}-propionic acid benzyl ester
CAS No.:148117-23-1
Molecular Formula:C₃₄H₄₅NO₇Si
Molecular Weight:607.819
Hs Code.:

Synonyms:(S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-phenoxy]-phenyl}-propionic acid benzyl ester

Suppliers and Price of (S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-phenoxy]-phenyl}-propionic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-phenoxy]-phenyl}-propionic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-phenoxy]-phenyl}-propionic acid benzyl ester

There total 5 articles about (S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-phenoxy]-phenyl}-propionic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 148117-22-0
(S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-hydroxy-phenoxy]-phenyl}-propionic acid benzyl ester

: 77-78-1
dimethyl sulfate

: 148117-23-1
(S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-phenoxy]-phenyl}-propionic acid benzyl ester

Guidance literature:: With potassium carbonate; In acetone; for 2h; Heating;
DOI:10.1016/0040-4039(93)85034-T

Reference yield:

: 3958-82-5
2-bromo-1,4-benzoquinone

: 148117-23-1
(S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-phenoxy]-phenyl}-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / KF / dimethylformamide / 90 °C

2: 100 percent / Na₂S₂O₄ / H₂O; CHCl₃ / 1 h / Ambient temperature

3: 80 percent / Et₃N / CH₂Cl₂ / 5 h / 0 °C

4: 87 percent / K₂CO₃ / acetone / 2 h / Heating

With potassium fluoride; sodium dithionite; potassium carbonate; triethylamine; In dichloromethane; chloroform; water; N,N-dimethyl-formamide; acetone;
DOI:10.1016/0040-4039(93)85034-T

Reference yield:

: 19391-35-6
N-tert-butoxycarbonyl-L-tyrosine benzyl ester

: 148117-23-1
(S)-2-tert-Butoxycarbonylamino-3-{4-[5-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-phenoxy]-phenyl}-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / KF / dimethylformamide / 90 °C

2: 100 percent / Na₂S₂O₄ / H₂O; CHCl₃ / 1 h / Ambient temperature

3: 80 percent / Et₃N / CH₂Cl₂ / 5 h / 0 °C

4: 87 percent / K₂CO₃ / acetone / 2 h / Heating

With potassium fluoride; sodium dithionite; potassium carbonate; triethylamine; In dichloromethane; chloroform; water; N,N-dimethyl-formamide; acetone;
DOI:10.1016/0040-4039(93)85034-T