trifluoro-methanesulfonic acid 6-(4-methoxy-2-methyl-phenyl)-pyridin-2-yl ester

Base Information

Chemical Name:trifluoro-methanesulfonic acid 6-(4-methoxy-2-methyl-phenyl)-pyridin-2-yl ester
CAS No.:521958-79-2
Molecular Formula:C₁₄H₁₂F₃NO₄S
Molecular Weight:347.315
Hs Code.:

Synonyms:trifluoro-methanesulfonic acid 6-(4-methoxy-2-methyl-phenyl)-pyridin-2-yl ester

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Chemical Property of trifluoro-methanesulfonic acid 6-(4-methoxy-2-methyl-phenyl)-pyridin-2-yl ester

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Technology Process of trifluoro-methanesulfonic acid 6-(4-methoxy-2-methyl-phenyl)-pyridin-2-yl ester

There total 2 articles about trifluoro-methanesulfonic acid 6-(4-methoxy-2-methyl-phenyl)-pyridin-2-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 358-23-6
trifluoromethylsulfonic anhydride

: 6-(4-methoxy-2-methyl-phenyl)-pyridin-2-ol

: 521958-79-2
trifluoro-methanesulfonic acid 6-(4-methoxy-2-methyl-phenyl)-pyridin-2-yl ester

Guidance literature:: With pyridine; at 20 ℃; for 0.5h;
DOI:10.1021/ol0272287

Reference yield:

: 521958-78-1
2-benzyloxy-6-(4-methoxy-2-methyl-phenyl)-pyridine

: 521958-79-2
trifluoro-methanesulfonic acid 6-(4-methoxy-2-methyl-phenyl)-pyridin-2-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / 10 percent Pd/C / ethanol / 4 h

2: 0.178 g / pyridine / 0.5 h / 20 °C

With pyridine; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/ol0272287