1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide

Base Information

• Chemical Name: 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide
• CAS No.: 70978-01-7
• Molecular Formula: C₁₉H₁₉N₅O₆S
• Molecular Weight: 445.456

Synonyms:1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide

Chemical Property of 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide

There total 3 articles about 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-Methoxybenzyl)-1H-tetrazole-5-carbonyl chloride (66492-66-8) + 1-(3-Amino-2-hydroxy-5-methanesulfonyl-phenyl)-ethanone (70977-88-7) → 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide (70978-01-7)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 1h; Yield given;

DOI:10.1021/jm00154a019

Reference yield:

potassium 1-(4-methoxyphenylmethyl)-1H-tetrazole-5-carboxylate (70977-77-4) → 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide (70978-01-7)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂, pyridine / toluene / 1 h / 20 °C

2: pyridine / CH₂Cl₂ / 1 h / 20 °C

With pyridine; thionyl chloride; In dichloromethane; toluene;

DOI:10.1021/jm00154a019

Reference yield:

→ 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide (70978-01-7)

Guidance literature:

entspr.Saeurechlorid,Anilin;

upstream raw materials:

1-(4-Methoxybenzyl)-1H-tetrazole-5-carbonyl chloride

1-(3-Amino-2-hydroxy-5-methanesulfonyl-phenyl)-ethanone

potassium 1-(4-methoxyphenylmethyl)-1H-tetrazole-5-carboxylate

Downstream raw materials:

1⁽²⁾H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 70978-01-7 1-(4-methoxy-benzyl)-1H-tetrazole-5-carboxylic acid 3-acetyl-2-hydroxy-5-methanesulfonyl-anilide

Send

Send

Metric Ton KG G Pound L ML

Send

Send