2,5-Piperazinedione,1-(methoxymethyl)-4-methyl-(9CI)

Base Information

Chemical Name:2,5-Piperazinedione,1-(methoxymethyl)-4-methyl-(9CI)
CAS No.:79247-68-0
Molecular Formula:C7H12 N2 O3
Molecular Weight:172.184
Hs Code.:
Mol file:79247-68-0.mol

Synonyms:2,5-Piperazinedione,1-(methoxymethyl)-4-methyl-(9CI);1-(METHOXYMETHYL)-4-METHYLPIPERAZINE-2,5-DION

Suppliers and Price of 2,5-Piperazinedione,1-(methoxymethyl)-4-methyl-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 2,5-Piperazinedione,1-(methoxymethyl)-4-methyl-(9CI)

Chemical Property:

PSA：49.85000
LogP:-1.23330

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,5-Piperazinedione,1-(methoxymethyl)-4-methyl-(9CI)

There total 1 articles about 2,5-Piperazinedione,1-(methoxymethyl)-4-methyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.6%

: 5625-52-5
1-methylpiperazin-2,5-dione

: 107-30-2
chloromethyl methyl ether

: 79247-68-0
1-Methoxymethyl-4-methyl-piperazine-2,5-dione

Guidance literature:: With potassium tert-butylate; In tert-butyl alcohol; at 0 ℃; for 0.166667h;
DOI:10.1016/S0040-4020(01)97960-8

Reference yield:

: 79247-68-0
1-Methoxymethyl-4-methyl-piperazine-2,5-dione

: 67-99-2,7762-12-1,61177-41-1
dl-Gliotoxin

Guidance literature:: Multi-step reaction with 16 steps

1: NBS, benzoylperoxide / CCl₄ / 1 h / Heating

2: CH₂Cl₂ / Ambient temperature

3: HCl / methanol / 0.67 h / 50 °C

4: BF₃-etherate / CH₂Cl₂ / Ambient temperature

5: conc. HCl / ethanol / 0.75 h / Heating

6: Triton B / CH₂Cl₂ / 0.5 h / Ambient temperature

7: 97.4 percent / pyridine / 1 h / Ambient temperature

8: TFA / 0.13 h / Ambient temperature

9: Et₃N / CH₂Cl₂ / 0.17 h / Ambient temperature

10: NaBH₄ / methanol; CH₂Cl₂ / 0.17 h / 0 °C

11: Et₃N / CH₂Cl₂ / 0.17 h / Ambient temperature

12: LiCl / dimethylformamide / 0.25 h / Ambient temperature

13: 94 percent / NaOMe / methanol; CH₂Cl₂ / 0.08 h / Ambient temperature

14: 52.3 percent / phenyllithium / tetrahydrofuran / 0.33 h / -78 °C

15: 59.8 percent / BCl₃ / CH₂Cl₂ / 0.17 h / 0 °C

16: 1.) m-ClPBA; 2.) (CH₃)2S, HClO₄ / 1.) CH₂Cl₂, 0 deg C, 10 min 2.) 9 h, r.t.

With pyridine; hydrogenchloride; sodium tetrahydroborate; N-Bromosuccinimide; perchloric acid; Perbenzoic acid; dimethylsulfide; boron trifluoride diethyl etherate; sodium methylate; boron trichloride; phenyllithium; triethylamine; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; lithium chloride; N-benzyl-trimethylammonium hydroxide; In tetrahydrofuran; methanol; tetrachloromethane; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)97960-8

Reference yield:

: 79247-68-0
1-Methoxymethyl-4-methyl-piperazine-2,5-dione

: 61377-99-9,79355-31-0,79355-32-1
Acetic acid (1S,6S)-5-hydroxymethyl-6-[(1R,3R,5R)-3-(4-methoxy-phenyl)-8-methyl-7,9-dioxo-2,4-dithia-6,8-diaza-bicyclo[3.2.2]non-6-yl]-cyclohexa-2,4-dienyl ester

Guidance literature:: Multi-step reaction with 10 steps

1: NBS, benzoylperoxide / CCl₄ / 1 h / Heating

2: CH₂Cl₂ / Ambient temperature

3: HCl / methanol / 0.67 h / 50 °C

4: BF₃-etherate / CH₂Cl₂ / Ambient temperature

5: conc. HCl / ethanol / 0.75 h / Heating

6: Triton B / CH₂Cl₂ / 0.5 h / Ambient temperature

7: 97.4 percent / pyridine / 1 h / Ambient temperature

8: TFA / 0.13 h / Ambient temperature

9: Et₃N / CH₂Cl₂ / 0.17 h / Ambient temperature

10: NaBH₄ / methanol; CH₂Cl₂ / 0.17 h / 0 °C

With pyridine; hydrogenchloride; sodium tetrahydroborate; N-Bromosuccinimide; Perbenzoic acid; boron trifluoride diethyl etherate; triethylamine; trifluoroacetic acid; N-benzyl-trimethylammonium hydroxide; In methanol; tetrachloromethane; ethanol; dichloromethane;
DOI:10.1016/S0040-4020(01)97960-8