1-methylpyrano[3,4-c]pyrazol-7(1H)-one

Base Information

Chemical Name:1-methylpyrano[3,4-c]pyrazol-7(1H)-one
CAS No.:79229-60-0
Molecular Formula:C₇H₆N₂O₂
Molecular Weight:150.137
Hs Code.:
DSSTox Substance ID:DTXSID00506936
Wikidata:Q82362916
Mol file:79229-60-0.mol

Synonyms:1-methylpyrano[3,4-c]pyrazol-7(1H)-one;79229-60-0;DTXSID00506936

Suppliers and Price of 1-methylpyrano[3,4-c]pyrazol-7(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-methylpyrano[3,4-c]pyrazol-7(1H)-one

Chemical Property:

PSA：48.03000
LogP:0.52650
XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:150.042927438
Heavy Atom Count:11
Complexity:215

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C=COC2=O)C=N1

Technology Process of 1-methylpyrano[3,4-c]pyrazol-7(1H)-one

There total 3 articles about 1-methylpyrano[3,4-c]pyrazol-7(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.5%

: 79229-66-6
4-ethynyl-1-methyl-1H-pyrazole-5-carboxylic acid

: 79229-60-0
1-Methyl-1H-pyrano[3,4-c]pyrazol-7-one

Guidance literature:: With copper(I) phenylacetylenide; In pyridine; Heating;
DOI:10.1007/BF00950297

Reference yield:

: 75092-26-1
4-iodo-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester

: 79229-60-0
1-Methyl-1H-pyrano[3,4-c]pyrazol-7-one

Guidance literature:: Multi-step reaction with 3 steps

1: 99.7 percent / CuI, Pd(PPh)3Cl₂ / diethylamine / 25 h / 50 °C

2: 1.) KOH, m-pentaphenyl ether, 2.) aq. KOH / 1.) 110 - 130 deg C, 1 mm Hg, 2.) 20 deg C, 48 h

3: 62.5 percent / PhCCCu / pyridine / Heating

With copper(I) phenylacetylenide; bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide; copper(l) iodide; m-pentaphenyl ether; In pyridine; diethylamine;
DOI:10.1007/BF00950297

Reference yield:

: 79229-74-6
4-(3-Hydroxy-3-phenyl-but-1-ynyl)-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester

: 79229-60-0
1-Methyl-1H-pyrano[3,4-c]pyrazol-7-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) KOH, m-pentaphenyl ether, 2.) aq. KOH / 1.) 110 - 130 deg C, 1 mm Hg, 2.) 20 deg C, 48 h

2: 62.5 percent / PhCCCu / pyridine / Heating

With copper(I) phenylacetylenide; potassium hydroxide; m-pentaphenyl ether; In pyridine;
DOI:10.1007/BF00950297