Technology Process of 2,5-bis(2-ethylhexyloxy)benzene-1,4-diboronic acid
There total 3 articles about 2,5-bis(2-ethylhexyloxy)benzene-1,4-diboronic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1,4-dibromo-2,5-bis((2-ethylhexyl)oxy)benzene;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 5.5h;
With
Triisopropyl borate;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
for 12h;
With
water;
In
tetrahydrofuran; hexane;
at 20 ℃;
for 2h;
Further stages.;
DOI:10.1021/ja012409+
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 74 percent / K2CO3 / dimethylformamide / 36 h / 100 °C
2.1: n-BuLi / tetrahydrofuran; hexane / 5.5 h / -78 °C
2.2: triisopropyl borate / tetrahydrofuran; hexane / 12 h / -78 - 20 °C
2.3: 38 percent / H2O / tetrahydrofuran; hexane / 2 h / 20 °C
With
n-butyllithium; potassium carbonate;
In
tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1021/ja012409+
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 74 percent / K2CO3 / dimethylformamide / 36 h / 100 °C
2.1: n-BuLi / tetrahydrofuran; hexane / 5.5 h / -78 °C
2.2: triisopropyl borate / tetrahydrofuran; hexane / 12 h / -78 - 20 °C
2.3: 38 percent / H2O / tetrahydrofuran; hexane / 2 h / 20 °C
With
n-butyllithium; potassium carbonate;
In
tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1021/ja012409+
