C₃₃H₄₉N₇O₁₁

Base Information

• Chemical Name: C₃₃H₄₉N₇O₁₁
• CAS No.: 1647150-54-6
• Molecular Formula: C₃₃H₄₉N₇O₁₁
• Molecular Weight: 719.792
• Mol file: 1647150-54-6.mol

Synonyms:C₃₃H₄₉N₇O₁₁

Chemical Property of C₃₃H₄₉N₇O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₄₉N₇O₁₁

There total 7 articles about C₃₃H₄₉N₇O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-azidopropyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-((R)-1-carboxyethyl)-β-D-glucopyranoside (1647150-53-5) + L-alanyl-D-isoglutamine tert-butyl ester (66025-76-1) → C33H49N7O11 (1647150-54-6)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

DOI:10.3762/bjoc.10.148

Reference yield:

D-isoGln(Ot-Bu) (70701-78-9) → C33H49N7O11 (1647150-54-6)

Guidance literature:

Multi-step reaction with 3 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 18 h

2: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 0.17 h

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 18 h / 20 °C

With benzotriazol-1-ol; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.3762/bjoc.10.148

Reference yield:

3-azidopropyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside → C33H49N7O11 (1647150-54-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / 1,4-dioxane; mineral oil / 1 h / 95 °C

1.2: 1.5 h / 65 °C

2.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 18 h / 20 °C

With sodium hydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; N,N-dimethyl-formamide; mineral oil;

DOI:10.3762/bjoc.10.148

upstream raw materials:

D-isoGln(Ot-Bu)

3-azidopropyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside

3-azidopropyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-((R)-1-carboxyethyl)-β-D-glucopyranoside

L-alanyl-D-isoglutamine tert-butyl ester

Downstream raw materials:

C₅₆H₇₂N₆O₁₆

C₅₃H₆₈N₆O₁₆