<2-(Trimethylsilyl)ethyl>-6-O-allyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid

Base Information

Chemical Name:<2-(Trimethylsilyl)ethyl>-6-O-allyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid
CAS No.:97604-71-2
Molecular Formula:C₂₈H₃₉N₃O₅Si
Molecular Weight:525.72
Hs Code.:

Synonyms:<2-(Trimethylsilyl)ethyl>-6-O-allyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid

Suppliers and Price of <2-(Trimethylsilyl)ethyl>-6-O-allyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of <2-(Trimethylsilyl)ethyl>-6-O-allyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of <2-(Trimethylsilyl)ethyl>-6-O-allyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid

There total 8 articles about <2-(Trimethylsilyl)ethyl>-6-O-allyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 97604-70-1
<2-(Trimethylsilyl)ethyl>-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid

: 106-95-6
allyl bromide

: 97604-71-2
<2-(Trimethylsilyl)ethyl>-6-O-allyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 15h; Ambient temperature;
DOI:10.1016/0008-6215(85)85193-4

Reference yield:

: 2916-68-9
2-(Trimethylsilyl)ethanol

: 97604-71-2
<2-(Trimethylsilyl)ethyl>-6-O-allyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid

Guidance literature:: Multi-step reaction with 6 steps

1: 79 percent / tetramethylurea / Ag-triflate / CH₂Cl₂ / 0.5 h / -45 °C

2: 97 percent / sodiummethoxide / methanol / 4 h / Ambient temperature

3: 86 percent / pyridine / 1 h / 80 °C

4: 89 percent / NaH / dimethylformamide / 2 h / Ambient temperature

5: 73 percent / aq. acetic acid / tetrahydrofuran / 2 h / 80 °C

6: 88 percent / NaH / dimethylformamide / 15 h / Ambient temperature

With pyridine; sodium methylate; sodium hydride; acetic acid; tetramethylurea; silver trifluoromethanesulfonate; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(85)85193-4

Reference yield:

: 95451-93-7
3,4,6-Tri-O-acetyl-2-azido-2-deoxy-α-D-mannopyranosyl bromide

: 97604-71-2
<2-(Trimethylsilyl)ethyl>-6-O-allyl-2-azido-3,4-di-O-benzyl-2-desoxy-α-D-mannopyranosid

Guidance literature:: Multi-step reaction with 6 steps

1: 79 percent / tetramethylurea / Ag-triflate / CH₂Cl₂ / 0.5 h / -45 °C

2: 97 percent / sodiummethoxide / methanol / 4 h / Ambient temperature

3: 86 percent / pyridine / 1 h / 80 °C

4: 89 percent / NaH / dimethylformamide / 2 h / Ambient temperature

5: 73 percent / aq. acetic acid / tetrahydrofuran / 2 h / 80 °C

6: 88 percent / NaH / dimethylformamide / 15 h / Ambient temperature

With pyridine; sodium methylate; sodium hydride; acetic acid; tetramethylurea; silver trifluoromethanesulfonate; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(85)85193-4