dibenzyl O-(1-O-methyl-2,4,6-tri-O-acetyl-β-D-galactopyranos-3-yl)phosphate

Base Information

• Chemical Name: dibenzyl O-(1-O-methyl-2,4,6-tri-O-acetyl-β-D-galactopyranos-3-yl)phosphate
• CAS No.: 945621-52-3
• Molecular Formula: C₂₇H₃₃O₁₂P
• Molecular Weight: 580.526
• Mol file: 945621-52-3.mol

Synonyms:dibenzyl O-(1-O-methyl-2,4,6-tri-O-acetyl-β-D-galactopyranos-3-yl)phosphate

Chemical Property of dibenzyl O-(1-O-methyl-2,4,6-tri-O-acetyl-β-D-galactopyranos-3-yl)phosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dibenzyl O-(1-O-methyl-2,4,6-tri-O-acetyl-β-D-galactopyranos-3-yl)phosphate

There total 6 articles about dibenzyl O-(1-O-methyl-2,4,6-tri-O-acetyl-β-D-galactopyranos-3-yl)phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

O,O-dibenzyl O-(1-O-methyl-2,4,6-tri-O-acetyl-β-D-galactopyranos-3-yl)phosphonate → dibenzyl O-(1-O-methyl-2,4,6-tri-O-acetyl-β-D-galactopyranos-3-yl)phosphate (945621-52-3)

Guidance literature:

With tert.-butylhydroperoxide; In decane; dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1080/07328300701351532

Reference yield:

methyl 3-O-benzyl-β-D-galactopyranoside (40010-11-5,61277-64-3,65942-01-0,81371-52-0,93714-01-3,108644-64-0,133268-63-0,133268-64-1,143005-10-1,143005-11-2,81371-53-1) → dibenzyl O-(1-O-methyl-2,4,6-tri-O-acetyl-β-D-galactopyranos-3-yl)phosphate (945621-52-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.35 g / pyridine / 20 °C

2: 97 percent / hydrogen / Pd/C / methanol / 2 h

3: tetrazole / CH₂Cl₂ / 20 °C

4: 75 percent / tert-butyl hydroperoxide / CH₂Cl₂; decane / 0.5 h / 20 °C

With pyridine; 1H-tetrazole; tert.-butylhydroperoxide; hydrogen; palladium on activated charcoal; In methanol; decane; dichloromethane;

DOI:10.1080/07328300701351532

Reference yield:

methyl 2,4,6-tri-O-acetyl-3-O-benzyl-β-D-galactopyranoside (81348-24-5) → dibenzyl O-(1-O-methyl-2,4,6-tri-O-acetyl-β-D-galactopyranos-3-yl)phosphate (945621-52-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / hydrogen / Pd/C / methanol / 2 h

2: tetrazole / CH₂Cl₂ / 20 °C

3: 75 percent / tert-butyl hydroperoxide / CH₂Cl₂; decane / 0.5 h / 20 °C

With 1H-tetrazole; tert.-butylhydroperoxide; hydrogen; palladium on activated charcoal; In methanol; decane; dichloromethane;

DOI:10.1080/07328300701351532

upstream raw materials:

methyl 3-O-benzyl-β-D-galactopyranoside

methyl 2,4,6-tri-O-acetyl-3-O-benzyl-β-D-galactopyranoside

methyl 2,4,6-tri-O-acetyl-β-D-galactopyranoside

methyl beta-D-galactopyranoside