D-threo-D-glycero-6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-3-hexosulitol

Base Information

Chemical Name:D-threo-D-glycero-6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-3-hexosulitol
CAS No.:260804-79-3
Molecular Formula:C₂₉H₄₂O₈Si
Molecular Weight:546.733
Hs Code.:

Synonyms:D-threo-D-glycero-6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-3-hexosulitol

Suppliers and Price of D-threo-D-glycero-6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-3-hexosulitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of D-threo-D-glycero-6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-3-hexosulitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of D-threo-D-glycero-6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-3-hexosulitol

There total 4 articles about D-threo-D-glycero-6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-3-hexosulitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 260804-78-2
6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-D-galactitol

: 260804-79-3
D-threo-D-glycero-6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-3-hexosulitol

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/jo982448c

Reference yield:

: 69602-93-3
5,6-O-isopropylidene-L-galactonic acid γ-lactone

: 260804-79-3
D-threo-D-glycero-6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-3-hexosulitol

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / iPr₂NEt; Bu₄NI / 3 h / 70 °C

2: 100 percent / LiAlH₄ / tetrahydrofuran / 1 h / 20 °C

3: 99.7 percent / iPr₂NEt; DMAP / CH₂Cl₂ / 1 h / 20 °C

4: 93 percent / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 20 °C

With dmap; lithium aluminium tetrahydride; tetra-(n-butyl)ammonium iodide; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; 1: Alkylation / 2: Reduction / 3: Substitution / 4: Oxidation;
DOI:10.1021/jo982448c

Reference yield:

: 260804-76-0
5,6-O-isopropylidene-2,3-di-O-methoxymethyl-L-galactono-γ-lactone

: 260804-79-3
D-threo-D-glycero-6-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-4,5-di-O-(methoxymethyl)-3-hexosulitol

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / LiAlH₄ / tetrahydrofuran / 1 h / 20 °C

2: 99.7 percent / iPr₂NEt; DMAP / CH₂Cl₂ / 1 h / 20 °C

3: 93 percent / Dess-Martin periodinane / CH₂Cl₂ / 2 h / 20 °C

With dmap; lithium aluminium tetrahydride; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; 1: Reduction / 2: Substitution / 3: Oxidation;
DOI:10.1021/jo982448c