N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(difluoromethoxy)-5-amino-4-nitro-benzoic acid amide

Base Information

Chemical Name:N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(difluoromethoxy)-5-amino-4-nitro-benzoic acid amide
CAS No.:1360624-52-7
Molecular Formula:C₁₅H₁₆F₅N₃O₄
Molecular Weight:397.302
Hs Code.:

Synonyms:N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(difluoromethoxy)-5-amino-4-nitro-benzoic acid amide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(difluoromethoxy)-5-amino-4-nitro-benzoic acid amide

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Technology Process of N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(difluoromethoxy)-5-amino-4-nitro-benzoic acid amide

There total 2 articles about N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(difluoromethoxy)-5-amino-4-nitro-benzoic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1073266-02-0
trans-4-(trifluoromethyl)cyclohexane-1-amine

: C₈H₅ClF₂N₂O₄

: 1360624-52-7
N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(difluoromethoxy)-5-amino-4-nitro-benzoic acid amide

Guidance literature:: With pyridine; In tetrahydrofuran; dichloromethane;

Reference yield:

: 1219014-87-5
2-(difluoro-methoxy)-5-amino-4-nitro-benzoic acid

: 1360624-52-7
N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-(difluoromethoxy)-5-amino-4-nitro-benzoic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: 1-chloro-1-(dimethylamino)-2-methyl-1-propene / dichloromethane; tetrahydrofuran / 5 h

2: pyridine / dichloromethane; tetrahydrofuran

With pyridine; 1-chloro-1-(dimethylamino)-2-methyl-1-propene; In tetrahydrofuran; dichloromethane;